土耳其马尔马拉地区一家大学医院3年期间门诊患者的维生素D水平

Vitamin D Levels of Outpatients Admitted to a University Hospital in the Marmara Region of Turkey Over 3 Years.

作者信息

Sezgin Gulbuz, Ozturk Guler, Turkal Rana, Caykara Burcu

机构信息

Department of Internal Medicine, Faculty of Medicine, Maltepe University, Istanbul, Turkey.

Department of Physiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.

出版信息

J Med Biochem. 2019 Mar 3;38(2):181-187. doi: 10.2478/jomb-2018-0027. eCollection 2019 Apr.

DOI:10.2478/jomb-2018-0027

PMID:30867646

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6410998/

Abstract

BACKGROUND

Vitamin D regulates calcium and phosphorus metabolism, and it is essential for bone formation. Several factors can affect vitamin D levels in plasma. In present study we compare vitamin D levels of outpatients, who admit to Maltepe University Hospital between 2011 and 2013 and had vitamin D measurements regarding gender, age, and season.

METHODS

Hospital records were evaluated to identify the outpatients with vitamin D levels and their gender, age, and vitamin D levels and the seasons of measurements were recorded.

RESULTS

Data of 4860 subjects (74% female) were analyzed and 69.2% were between 18-64 years old. Vitamin D levels were as follows: 43.1% ≤ 10 ng/mL, 31.9% between 10 ng/mL and 20 ng/mL, 16.1% between 20 ng/mL and 30 ng/mL, and only 8.9% ≥ 30 ng/mL. The number of females with vitamin D levels < 10 ng/mL was significantly higher than that of males, while the number of males with vitamin D levels between 10 ng/mL and 20 ng/mL was significantly higher than that of females (P = 0.001) for each of the individuals, 6.2% and 11.1% had sufficient levels in winter and summer, respectively. Overall, it was observed that 6.6% of individuals between 18-44 years old, 8.2% of individuals between 45-64 years old and 10.3% of individuals over 65 years old had vitamin D levels > 30 ng/mL.

CONCLUSIONS

The prevalence of vitamin D deficiency in outpatients of Maltepe University Hospital in Marmara region was 75% (< 20 ng/mL).

摘要

背景

维生素D调节钙和磷的代谢，对骨骼形成至关重要。多种因素可影响血浆中维生素D的水平。在本研究中，我们比较了2011年至2013年间入住马尔泰佩大学医院且进行了维生素D检测的门诊患者的维生素D水平，涉及性别、年龄和季节因素。

方法

评估医院记录以确定有维生素D水平检测结果的门诊患者及其性别、年龄，并记录维生素D水平和检测季节。

结果

分析了4860名受试者的数据（74%为女性），69.2%的受试者年龄在18 - 64岁之间。维生素D水平如下：43.1%≤10 ng/mL，31.9%在10 ng/mL至20 ng/mL之间，16.1%在20 ng/mL至30 ng/mL之间，仅8.9%≥30 ng/mL。维生素D水平<10 ng/mL的女性数量显著高于男性，而维生素D水平在10 ng/mL至20 ng/mL之间的男性数量显著高于女性（P = 0.001）。对于每个个体，冬季和夏季维生素D水平充足的比例分别为6.2%和11.1%。总体而言，观察到18 - 44岁的个体中有6.6%、45 - 64岁的个体中有8.2%以及65岁以上的个体中有10.3%的维生素D水平>30 ng/mL。