Sezgin Gulbuz, Ozturk Guler, Turkal Rana, Caykara Burcu
Department of Internal Medicine, Faculty of Medicine, Maltepe University, Istanbul, Turkey.
Department of Physiology, Faculty of Medicine, Istanbul Medeniyet University, Istanbul, Turkey.
J Med Biochem. 2019 Mar 3;38(2):181-187. doi: 10.2478/jomb-2018-0027. eCollection 2019 Apr.
Vitamin D regulates calcium and phosphorus metabolism, and it is essential for bone formation. Several factors can affect vitamin D levels in plasma. In present study we compare vitamin D levels of outpatients, who admit to Maltepe University Hospital between 2011 and 2013 and had vitamin D measurements regarding gender, age, and season.
Hospital records were evaluated to identify the outpatients with vitamin D levels and their gender, age, and vitamin D levels and the seasons of measurements were recorded.
Data of 4860 subjects (74% female) were analyzed and 69.2% were between 18-64 years old. Vitamin D levels were as follows: 43.1% ≤ 10 ng/mL, 31.9% between 10 ng/mL and 20 ng/mL, 16.1% between 20 ng/mL and 30 ng/mL, and only 8.9% ≥ 30 ng/mL. The number of females with vitamin D levels < 10 ng/mL was significantly higher than that of males, while the number of males with vitamin D levels between 10 ng/mL and 20 ng/mL was significantly higher than that of females (P = 0.001) for each of the individuals, 6.2% and 11.1% had sufficient levels in winter and summer, respectively. Overall, it was observed that 6.6% of individuals between 18-44 years old, 8.2% of individuals between 45-64 years old and 10.3% of individuals over 65 years old had vitamin D levels > 30 ng/mL.
The prevalence of vitamin D deficiency in outpatients of Maltepe University Hospital in Marmara region was 75% (< 20 ng/mL).
维生素D调节钙和磷的代谢，对骨骼形成至关重要。多种因素可影响血浆中维生素D的水平。在本研究中，我们比较了2011年至2013年间入住马尔泰佩大学医院且进行了维生素D检测的门诊患者的维生素D水平，涉及性别、年龄和季节因素。
评估医院记录以确定有维生素D水平检测结果的门诊患者及其性别、年龄，并记录维生素D水平和检测季节。
分析了4860名受试者的数据（74%为女性），69.2%的受试者年龄在18 - 64岁之间。维生素D水平如下：43.1%≤10 ng/mL，31.9%在10 ng/mL至20 ng/mL之间，16.1%在20 ng/mL至30 ng/mL之间，仅8.9%≥30 ng/mL。维生素D水平<10 ng/mL的女性数量显著高于男性，而维生素D水平在10 ng/mL至20 ng/mL之间的男性数量显著高于女性（P = 0.001）。对于每个个体，冬季和夏季维生素D水平充足的比例分别为6.2%和11.1%。总体而言，观察到18 - 44岁的个体中有6.6%、45 - 64岁的个体中有8.2%以及65岁以上的个体中有10.3%的维生素D水平>30 ng/mL。
马尔马拉地区马尔泰佩大学医院门诊患者中维生素D缺乏的患病率为75%（<20 ng/mL）。
