即将问世的局部用脂质体药物：专利文献告诉了我们什么。综述。

Topical liposome drugs to come: what the patent literature tells us. A review.

作者信息

Korting H C, Blecher P, Schäfer-Korting M, Wendel A

机构信息

Dermatologische Klinik und Poliklinik, Ludwig-Maximilians-Universität, Münich, Germany.

出版信息

J Am Acad Dermatol. 1991 Dec;25(6 Pt 1):1068-71. doi: 10.1016/0190-9622(91)70309-p.

DOI:10.1016/0190-9622(91)70309-p

PMID:1810984

Abstract

Drug-containing liposomes for topical use in dermatology have been devised during the last 10 years. Most recently the clinical superiority to a conventional gel of a topical glucocorticosteroid liposome preparation for eczema has been demonstrated. To get more insight from what may be expected from future liposome preparations for topical treatment, the pertinent patent literature has been reviewed.

摘要

含药脂质体用于皮肤科局部用药是在过去10年中设计出来的。最近，一种用于治疗湿疹的局部糖皮质激素脂质体制剂已被证明在临床上优于传统凝胶。为了更深入了解未来用于局部治疗的脂质体制剂可能带来的效果，我们对相关专利文献进行了综述。