Kem W R, Scott K N, Duncan J H
Experientia. 1976 Jun 15;32(6):684-6. doi: 10.1007/BF01919831.
Two pyridine bases were isolated from the marine hoplonemertine Amphiporus angulatus (Fabricius) and identified by mass and PMR-spectroscopy as 2, 3'-bipyridyl and 3, 2'; 3', 2"; 4", 3"'-tetrapyridyl (Nemertelline). Nemertelline, the first tetrapyridyl natural product to be reported, shows a structural resemblance to the tobacco constituent nicotelline. The crustacean toxicity of 2, 3' -bipyridyl is very similar to that of nicotine, but its mammalian toxicity is negligible.
从海洋刺胞纽虫角形歧肠纽虫(Fabricius)中分离出两种吡啶碱,并通过质谱和核磁共振光谱鉴定为2, 3'-联吡啶和3, 2'; 3', 2"; 4", 3"'-四吡啶(纽虫碱)。纽虫碱是首个被报道的四吡啶天然产物,其结构与烟草成分烟碱相似。2, 3'-联吡啶对甲壳类动物的毒性与尼古丁非常相似,但其对哺乳动物的毒性可忽略不计。