Arslan Seher Gündüz, Akpolat Nezahat, Kama Jalan Devecioğlu, Ozer Törün, Hamamci Orhan
Department of Orthodontics, Dental Faculty, Dicle University Diyarbakier, Turkey.
J Oral Pathol Med. 2008 Jan;37(1):26-9. doi: 10.1111/j.1600-0714.2007.00574.x.
The aim of this study was to assess quantitative and qualitative alterations in the carrier rate of Candida spp. in south-eastern Turkey among adolescents, and to investigate the effect of fixed orthodontic appliances on the Candida count in a 1-year follow-up study. In the first phase of the study, the oral Candida carriage rate of 72 patients was evaluated. Samples were collected from the dorsal surface of the tongue, the mid-palate and saliva. In the second phase of the study, 42 patients who were determined to be carriers of oral Candida were treated with fixed orthodontic appliances, and from these patients a second set of samples were collected from the saliva and the orthodontic brace surfaces of eight teeth adjacent to the enamel surfaces. The saliva samples were collected before and during orthodontic treatment at 1st, 6th and 12th month, and samples from the braces were collected during the 1st, 6th and 12th month of treatment. Forty-two of the 72 patients (58.5%) were oral Candida carriers. The distribution of Candida spp. in these patients was as follows: (i) Candida albicans was identified in 31 patients (73.8%), (ii) C. tropicalis, C. krusei and C. kefyr were found in three patients each (7.14%) and (iii) C. parapsilosis occurred in two patients (4.76%). During orthodontic treatment, the micro-organism count increased both in the saliva and on tooth surfaces. The results indicate that the prevalence of oral Candida spp. is high in young adults in south-eastern Turkey and that the Candida counts increase when braces are involved.
本研究旨在评估土耳其东南部青少年念珠菌属携带率的定量和定性变化，并在一项为期1年的随访研究中调查固定正畸矫治器对念珠菌计数的影响。在研究的第一阶段，评估了72例患者的口腔念珠菌携带率。样本采集自舌背、腭中部和唾液。在研究的第二阶段，对42例被确定为口腔念珠菌携带者的患者使用固定正畸矫治器进行治疗，并从这些患者的唾液以及与牙釉质表面相邻的8颗牙齿的正畸托槽表面采集第二组样本。唾液样本在正畸治疗前以及治疗第1、6和12个月时采集，托槽样本在治疗第1、6和12个月时采集。72例患者中有42例（58.5%）为口腔念珠菌携带者。这些患者中念珠菌属的分布如下：（i）31例患者（73.8%）鉴定为白色念珠菌，（ii）热带念珠菌、克柔念珠菌和光滑念珠菌各在3例患者中发现（7.14%），（iii）近平滑念珠菌在2例患者中出现（4.76%）。在正畸治疗期间，唾液和牙齿表面的微生物计数均增加。结果表明，土耳其东南部年轻成年人中口腔念珠菌属的患病率较高，并且使用矫治器时念珠菌计数会增加。
