Lu Ju, Lichtman Jeff W
Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.
Sheng Li Xue Bao. 2007 Dec 25;59(6):683-96.
The neuromuscular junction (NMJ) has been studied for over a century as a model system for synaptic anatomy, physiology and development. Much of our knowledge of the NMJ has been obtained through imaging techniques, some of which were developed particularly to visualize this synapse's structure and function. In this paper we review the historical development of research on some key aspects of the NMJ, including its structure, nicotinic acetylcholine receptor distribution, the process of synaptic vesicle release, and its development.
神经肌肉接头（NMJ）作为突触解剖学、生理学和发育的模型系统，已经被研究了一个多世纪。我们对神经肌肉接头的许多认识都是通过成像技术获得的，其中一些技术是专门为可视化这个突触的结构和功能而开发的。在本文中，我们回顾了神经肌肉接头一些关键方面的研究历史发展，包括其结构、烟碱型乙酰胆碱受体分布、突触小泡释放过程及其发育。
