De Ferranti Sarah D, Osganian Stavroula K
Preventive Cardiology Clinic, Department of Cardiology, Children's Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA.
Diab Vasc Dis Res. 2007 Dec;4(4):285-96. doi: 10.3132/dvdr.2007.055.
The epidemic in childhood obesity is a driving force behind the increase in paediatric metabolic syndrome, a collection of abnormalities that is associated in adults with increased risk for cardiovascular disease and type 2 diabetes mellitus. Although there is no clear consensus about the paediatric definition for metabolic syndrome, the prevalence of this syndrome is clearly rising. Children with metabolic syndrome are at increased risk for metabolic syndrome in adulthood. A late consequence of metabolic syndrome is type 2 diabetes, which increasingly affects adolescents. The rise in metabolic syndrome and type 2 diabetes in children is almost sure to lead to an increase in associated complications in young adulthood, including early cardiovascular disease. This epidemic will bear fruit in forthcoming decades, putting further stress on the healthcare system and probably leading to increased morbidity and a shorter lifespan for future generations.
儿童肥胖流行是小儿代谢综合征增加的一个推动因素，代谢综合征是一系列异常情况，在成人中与心血管疾病和2型糖尿病风险增加相关。尽管对于代谢综合征的儿科定义尚无明确共识，但该综合征的患病率显然在上升。患有代谢综合征的儿童成年后患代谢综合征的风险增加。代谢综合征的一个晚期后果是2型糖尿病，该病对青少年的影响越来越大。儿童代谢综合征和2型糖尿病的增加几乎肯定会导致青年期相关并发症的增加，包括早期心血管疾病。这种流行在未来几十年将产生后果，给医疗系统带来进一步压力，并可能导致后代发病率增加和寿命缩短。
