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新兴传染病快速研究应对资金方面的创新与挑战:严重急性呼吸系统综合征爆发带来的经验教训。

Innovation and challenges in funding rapid research responses to emerging infectious diseases: Lessons learned from the outbreak of severe acute respiratory syndrome.

机构信息

Institute of Infection and Immunity, Canadian Institutes of Health Research; Department of Microbiology and Immunology, University of Western Ontario, London, Ontario.

出版信息

Can J Infect Dis Med Microbiol. 2004 May;15(3):167-70. doi: 10.1155/2004/925872.

DOI:10.1155/2004/925872
PMID:18159488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2094971/
Abstract

Although the local public health response to the severe acute respiratory syndrome outbreak in Canada was critical to the diagnosis, management and treatment of patients, such a rapid research response required a national effort to engage the research and stakeholder communities. The Canadian research effort, coordinated through the Institute of Infection and Immunity of the Canadian Institutes of Health Research and the Michael Smith Foundation for Health Research, has provided insight into the mechanisms required to ensure the rapid development of strategical initiatives in response to emerging infectious diseases. It has also provided a rational basis to set up a national network to be engaged if needed in the future.

摘要

尽管加拿大对严重急性呼吸系统综合征疫情的地方公共卫生反应对患者的诊断、管理和治疗至关重要,但如此迅速的研究反应需要全国范围内的努力来吸引研究和利益相关者社区的参与。加拿大的研究工作通过加拿大卫生研究院感染与免疫研究所和迈克尔·史密斯基金会健康研究协调进行,深入了解了确保快速制定战略举措应对新出现的传染病所需的机制。它还为建立一个国家网络提供了合理的依据,如果需要,该网络可以在未来参与其中。

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本文引用的文献

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Science. 2004 Mar 12;303(5664):1605. doi: 10.1126/science.303.5664.1605.
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Medicine. Caution urged on SARS vaccines.医学。对非典疫苗发出谨慎呼吁。
Science. 2004 Feb 13;303(5660):944-6. doi: 10.1126/science.303.5660.944.
3
Severe acute respiratory syndrome: developing a research response.严重急性呼吸综合征:制定研究应对措施。
J Infect Dis. 2004 Feb 15;189(4):634-41. doi: 10.1086/382225. Epub 2004 Jan 28.
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Interferon alfacon-1 plus corticosteroids in severe acute respiratory syndrome: a preliminary study.干扰素 alfacon-1 联合皮质类固醇治疗严重急性呼吸综合征:一项初步研究。
JAMA. 2003 Dec 24;290(24):3222-8. doi: 10.1001/jama.290.24.3222.
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SARS: what have we learned?严重急性呼吸综合征:我们学到了什么?
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The Genome sequence of the SARS-associated coronavirus.与严重急性呼吸综合征相关的冠状病毒的基因组序列。
Science. 2003 May 30;300(5624):1399-404. doi: 10.1126/science.1085953. Epub 2003 May 1.
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Identification of severe acute respiratory syndrome in Canada.加拿大严重急性呼吸综合征的识别。
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