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研究准备为应对 2009 年甲型 H1N1 流感病毒铺平了道路。

Research preparedness paves the way to respond to pandemic H1N1 2009 influenza virus.

机构信息

University of Toronto, Toronto;

出版信息

Can J Infect Dis Med Microbiol. 2009 Fall;20(3):63-e66. doi: 10.1155/2009/798387.

DOI:10.1155/2009/798387
PMID:20808463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2770297/
Abstract

The international community has been preparing for an influenza pandemic because of the threat posed by H5N1 avian influenza. Over the past several years, Canada has dedicated funding to boost capacity for research, and public health and health care system readiness and response in the event of a pandemic. The current H1N1/09 influenza pandemic is now testing our readiness. From a research perspective, the present commentary discusses how have we prepared, along with the research gaps. We conclude that: sources of pandemics are not always predictable; investment in the past few years has paid off in a rapid response to pandemic H1N1/09 virus in Canada; and research to meet the challenges of infectious diseases has to be done on an ongoing long-term basis, and its funding has to be flexible, available and predictable to maintain capacity and expertise. In addition, new vaccine technologies are needed to develop and produce vaccines for public health emergencies in a timely fashion.

摘要

由于 H5N1 禽流感的威胁,国际社会一直在为流感大流行做准备。在过去的几年中,加拿大专门拨出资金,以提高研究能力,以及公共卫生和卫生保健系统在大流行情况下的准备和应对能力。当前的 H1N1/09 流感大流行正在考验我们的准备情况。从研究的角度来看,本评论讨论了我们是如何准备的,以及存在的研究差距。我们的结论是:大流行的源头并不总是可以预测的;过去几年的投资在加拿大对 H1N1/09 病毒大流行的快速反应中得到了回报;应对传染病挑战的研究必须在长期基础上进行,其资金必须具有灵活性、可用性和可预测性,以保持能力和专业知识。此外,需要开发新的疫苗技术,以便及时为公共卫生紧急情况生产疫苗。

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本文引用的文献

1
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CMAJ. 2009 Sep 15;181(6-7):E108. doi: 10.1503/cmaj.109-3014.
2
Swine flu outbreak tests Canadian preparedness.猪流感疫情考验加拿大的防范能力。
CMAJ. 2009 Jun 9;180(12):E93-4. doi: 10.1503/cmaj.090805.
3
Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans.在人群中传播的源自猪的2009年甲型H1N1流感病毒的抗原和基因特征
Science. 2009 Jul 10;325(5937):197-201. doi: 10.1126/science.1176225. Epub 2009 May 22.
4
Swine flu outbreak. What role for antiviral drugs?猪流感爆发。抗病毒药物起什么作用?
Science. 2009 May 8;324(5928):705. doi: 10.1126/science.324_705.
5
Swine influenza: how much of a global threat?猪流感:对全球构成多大威胁?
Lancet. 2009 May 2;373(9674):1495. doi: 10.1016/S0140-6736(09)60826-6.
6
Mathematical assessment of Canada's pandemic influenza preparedness plan.加拿大大流行性流感防备计划的数学评估。
Can J Infect Dis Med Microbiol. 2008 Mar;19(2):185-92. doi: 10.1155/2008/538975.
7
Innovation and challenges in funding rapid research responses to emerging infectious diseases: Lessons learned from the outbreak of severe acute respiratory syndrome.新兴传染病快速研究应对资金方面的创新与挑战:严重急性呼吸系统综合征爆发带来的经验教训。
Can J Infect Dis Med Microbiol. 2004 May;15(3):167-70. doi: 10.1155/2004/925872.
8
1918 Influenza: the mother of all pandemics.1918年流感:所有大流行之母。
Emerg Infect Dis. 2006 Jan;12(1):15-22. doi: 10.3201/eid1201.050979.
9
Rapid response research to emerging infectious diseases: lessons from SARS.对新发传染病的快速反应研究:非典带来的教训。
Nat Rev Microbiol. 2004 Jul;2(7):602-7. doi: 10.1038/nrmicro930.
10
The Genome sequence of the SARS-associated coronavirus.与严重急性呼吸综合征相关的冠状病毒的基因组序列。
Science. 2003 May 30;300(5624):1399-404. doi: 10.1126/science.1085953. Epub 2003 May 1.