Nasseri Kiumarss, Mills Paul K, Allan Mark
Publi Health Institute, Tri-Counties Cancer Surveillance Program, CA, USA.
Asian Pac J Cancer Prev. 2007 Jul-Sep;8(3):405-11.
International statistics suggest lower cancer incidence in the Middle East and Middle Eastern (ME) immigrants in Europe, Australia, and Canada, but little is known from the United States. This study compares cancer rates in ME population with other race/ethnic groups in California from 1988 through 2004. ME cases in California cancer registry were identified by surname and ME population was estimated from U.S. Census data. Cancer rates for ME countries was obtained from Globocan. The ME incidence rate ratios for all sites combined in male and female were 0.77 and 0.82, respectively and were statistically significant. ME rates were significantly lower for cancers of the colon, lung, skin melanoma, female breast and prostate, and were significantly higher for cancers of the stomach, liver, thyroid, leukemia, and male breast. Cancer incidence in ME population in California was 2.4 times higher than rates in home countries. Incidence trends in ME males remained fairly stable but in females shows a slight decline in recent years. Cancer incidence in ME population is lower than non-Hispanic white and non-Hispanic Black, but is higher than rates for Hispanics and Asians, and ME countries. Improved data quality, chronic infections, acculturation, and access to screening services are some of the factors responsible for the observed pattern.
国际统计数据显示，中东地区以及在欧洲、澳大利亚和加拿大的中东移民的癌症发病率较低，但美国的相关情况鲜为人知。本研究比较了1988年至2004年加利福尼亚州中东人群与其他种族/族裔群体的癌症发病率。通过姓氏确定加利福尼亚癌症登记处中的中东病例，并根据美国人口普查数据估算中东人口。中东国家的癌症发病率数据来自全球癌症发病率数据库（Globocan）。男性和女性所有部位癌症的中东发病率比值分别为0.77和0.82，具有统计学意义。中东人群结肠癌、肺癌、皮肤黑色素瘤、女性乳腺癌和前列腺癌的发病率显著较低，而胃癌、肝癌、甲状腺癌、白血病和男性乳腺癌的发病率则显著较高。加利福尼亚州中东人群的癌症发病率比其原籍国高2.4倍。中东男性的发病率趋势保持相当稳定，但女性近年来略有下降。中东人群的癌症发病率低于非西班牙裔白人和非西班牙裔黑人，但高于西班牙裔和亚裔以及中东国家。数据质量的提高、慢性感染、文化适应以及筛查服务的可及性是造成观察到的这种模式的部分因素。
