Rukachaisirikul Thitima, Innok Phongsak, Suksamrarn Apichart
Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok, Thailand.
J Nat Prod. 2008 Jan;71(1):156-8. doi: 10.1021/np070506w. Epub 2008 Jan 3.
Three new erythrina alkaloids, (+)-10,11-dioxoerythratine (1), (+)-10,11-dioxoepierythratidine (2), and (+)-10,11-dioxoerythratidinone (3), and a new pterocarpan, 1-methoxyerythrabyssin II (4), were isolated from the bark of Erythrina subumbrans, together with seven known pterocarpans, erythrabyssin II, erybraedin A, erystagallin A, erycristagallin, erythrabissin-1, eryvarin A, and hydroxycristacarpone, three flavanones, 5-hydroxysophoranone, abyssinone V, and lespedezaflavanone B, three triterpenes, sophoradiol, soyasapogenol B, and lupeol, and one isoflavanone, vogelin C. Their structures were elucidated on the basis of spectroscopic data. Some isolates were tested for antiplasmodial, antimycobacterial, and cytotoxic activities.
从刺桐（Erythrina subumbrans）树皮中分离出三种新的刺桐生物碱，即(+)-10,11-二氧代刺桐亭（1）、(+)-10,11-二氧代表刺桐定（2）和(+)-10,11-二氧代刺桐啶酮（3），以及一种新的紫檀素，1-甲氧基刺桐苦素II（4），同时还分离出七种已知的紫檀素，即刺桐苦素II、刺桐素A、刺桐黄烷醇A、刺桐晶黄酮、刺桐双素-1、刺桐黄素A和羟基刺桐酮，三种黄烷酮，即5-羟基槐酮、阿比西酮V和胡枝子黄烷酮B，三种三萜，即槐二醇、大豆皂醇B和羽扇豆醇，以及一种异黄烷酮，即沃吉林C。根据光谱数据阐明了它们的结构。对一些分离物进行了抗疟原虫、抗分枝杆菌和细胞毒性活性测试。
