Wang Shuang, Xu Liang, Wang Yunshong, Wang Yaxing, Jonas Jost B
Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, China.
Clin Exp Ophthalmol. 2007 Dec;35(9):800-7. doi: 10.1111/j.1442-9071.2007.01627.x.
To assess retinal vessel diameter in adult Chinese with and without glaucoma.
The population-based, cross-sectional study included 4439 of the 5324 subjects asked to participate (response rate 83.4%), all aged 40 years or older. This study was divided into a rural part (1973 subjects [44.4%]) and an urban part (2466 subjects [55.6%]). Colour optic disc and fundus photographs were morphometrically examined for 2418 subjects. The retinal vessel diameters were measured at the optic disc border and at a distance of 2 mm to the optic disc border. The main outcome measure was the retinal vessel diameter.
Diameters of the retinal arteries were significantly (P < 0.001) the widest in the temporal inferior region, followed by the temporal superior region (P < 0.001), the nasal superior region (P < 0.001) and finally the nasal inferior region. Except for the nasal inferior vein, the same held true for the retinal veins. The sequence of the main four vessel trunks with respect to their diameters was not associated with age, gender or hyperopia versus myopia. The artery diameters showed a tendency to decrease in older age, while the vein diameters decreased across all age groups. Eyes with glaucomatous optic nerve damage showed significantly (P < 0.001) thinner arteries while the retinal vein diameters were not different.
Diameters of the retinal arterioles and veins are the widest in the temporal inferior arcade, followed by the temporal superior arcade, the nasal superior arcade and finally the nasal inferior arcade. Retinal artery diameters decrease with glaucoma, and retinal vein diameters decrease with age.
评估患有和未患有青光眼的成年中国人的视网膜血管直径。
这项基于人群的横断面研究纳入了5324名受邀参与者中的4439名（应答率83.4%），所有参与者年龄均在40岁及以上。本研究分为农村部分（1973名受试者[44.4%]）和城市部分（2466名受试者[55.6%]）。对2418名受试者的彩色视盘和眼底照片进行形态测量检查。在视盘边界以及距视盘边界2毫米处测量视网膜血管直径。主要观察指标为视网膜血管直径。
视网膜动脉直径在颞下区域最宽，差异有统计学意义（P<0.001），其次是颞上区域（P<0.001）、鼻上区域（P<0.001），最后是鼻下区域。除鼻下静脉外，视网膜静脉情况相同。四条主要血管干直径的顺序与年龄、性别或远视与近视无关。动脉直径在老年时有减小趋势，而静脉直径在所有年龄组中均减小。患有青光眼性视神经损伤的眼睛动脉明显更细（P<0.001），而视网膜静脉直径无差异。
视网膜小动脉和静脉直径在颞下弓最宽，其次是颞上弓、鼻上弓，最后是鼻下弓。视网膜动脉直径随青光眼而减小，视网膜静脉直径随年龄而减小。
