Yu Bing, Tuo Ya, Gui Hong-sheng, Li Sheng-bin
Key Laboratory of Forensic Sciences, National Ministry of Health, Xi'an Jiaotong University, Xi'an, 710061 China.
Fa Yi Xue Za Zhi. 2007 Oct;23(5):342-4.
To validate the genetic characteristics and distribution of DXS7424-DXS101 on X chromosome in Han population.
DXS7424 and DXS101 loci were genotyped by PCR, PAGE and silvers stain methods. Their genetic parameters were analyzed by Arlequin software.
There were 37 haplotypes detected in 151 Han unrelated males. The frequencies ranged from 0.0066 to 0.1391, with a GD value of 0.9453 and a DP value of 0.9389. Haplotypes 16-23 were the most common haplotypes in Han population.
Analysis of combined DXS7424 and DXS101 haplotypes appears to be a powerful means in population genetics and forensic practice for determination of identity and paternity.
验证DXS7424 - DXS101在汉族人群X染色体上的遗传特征及分布情况。
采用聚合酶链反应（PCR）、聚丙烯酰胺凝胶电泳（PAGE）及银染法对DXS7424和DXS101基因座进行基因分型。利用Arlequin软件分析其遗传参数。
在151名汉族无关男性中检测到37种单倍型。频率范围为0.0066至0.1391，基因多样性（GD）值为0.9453，个人识别力（DP）值为0.9389。单倍型16 - 23是汉族人群中最常见的单倍型。
联合分析DXS7424和DXS101单倍型似乎是群体遗传学和法医学实践中用于身份鉴定和亲子鉴定的有力手段。
