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五肽胃泌素、组胺、胰高血糖素、促胰液素和高氯酸盐对小鼠胃处理99m锝高锝酸盐的影响。

Effect of pentagastrin, histalog, glucagon, secretin, and perchlorate on the gastric handling of 99mTc pertechnetate in mice.

作者信息

Khettery J, Effmann E, Grand R J, Treves S

出版信息

Radiology. 1976 Sep;120(3):629-31. doi: 10.1148/120.3.629.

DOI:10.1148/120.3.629
PMID:181784
Abstract

Pentagastrin, histalog, glucagon, secretin, and perchlorate were intravenously injected into mice in order to investigate the hormonal regulation of 99mTc pertechnetate uptake by gastric mucosa. Pentagastrin significantly increased uptake; the effect of histalog was weaker. Secretin did not alter the uptake. Glucagon produced some diminution, and perchlorate significantly inhibited gastric uptake. Hormones may play a role in improving the sensitivity and specificity of diagnostic tests for Meckel's diverticulum.

摘要

为了研究胃黏膜对高锝酸盐摄取的激素调节作用,将五肽胃泌素、组胺、胰高血糖素、促胰液素和高氯酸盐静脉注射到小鼠体内。五肽胃泌素显著增加摄取量;组胺的作用较弱。促胰液素未改变摄取量。胰高血糖素使摄取量有所减少,高氯酸盐显著抑制胃摄取。激素可能在提高梅克尔憩室诊断试验的敏感性和特异性方面发挥作用。

相似文献

1
Effect of pentagastrin, histalog, glucagon, secretin, and perchlorate on the gastric handling of 99mTc pertechnetate in mice.五肽胃泌素、组胺、胰高血糖素、促胰液素和高氯酸盐对小鼠胃处理99m锝高锝酸盐的影响。
Radiology. 1976 Sep;120(3):629-31. doi: 10.1148/120.3.629.
2
Hormonal enhancement of technetium-99m pertechnetate uptake in experimental Meckel's diverticulum.实验性梅克尔憩室中激素对高锝[99mTc]酸盐摄取的增强作用。
J Pediatr Surg. 1980 Dec;15(6):900-5. doi: 10.1016/s0022-3468(80)80301-0.
3
Radionuclide imaging of Meckel's diverticulum: cimetidine versus pentagastrin plus glucagon.梅克尔憩室的放射性核素显像:西咪替丁与五肽胃泌素加胰高血糖素的比较
Eur J Nucl Med. 1984;9(7):316-9. doi: 10.1007/BF00276461.
4
Pentagastrin stimulation of technetium-99m uptake by ectopic gastric muscosa in a Meckel's diverticulum.五肽胃泌素刺激梅克尔憩室中异位胃黏膜摄取锝-99m。
Radiology. 1978 Sep;128(3):711-2. doi: 10.1148/128.3.711.
5
Development of gastric acid secretion in pigs from birth to thirty six days of age: the response to pentagastrin.仔猪从出生到36日龄胃酸分泌的发育:对五肽胃泌素的反应。
J Dev Physiol. 1990 Jun;13(6):315-26.
6
The effect of gastrointestinal hormones on the pertechnetate imaging of ectopic gastric mucosa in experimental Meckel's diverticulum.胃肠道激素对实验性梅克尔憩室异位胃黏膜高锝酸盐显像的影响。
J Nucl Med. 1981 Aug;22(8):678-83.
7
[Effect of gastrointestinal hormones on gastric mucosa with special regard to the regulation of its electric potential. III. Studies of electric potential of gastric mucosa in rats. Hormonal regulation of gastric electric potential. Relationship between gastric electric potential changes after pentagastrin and gastric juice secretion and ultrastructure of parietal cells].[胃肠激素对胃黏膜的作用,特别关注其电位调节。III. 大鼠胃黏膜电位研究。胃电位的激素调节。五肽胃泌素后胃电位变化与胃液分泌及壁细胞超微结构的关系]
Folia Med Cracov. 1979;21(3):369-85.
8
Inhibitory effect of glucagon, secretin and caerulein on gastric acid secretion stimulated by pentagastrin in patients with duodenal ulcer.胰高血糖素、促胰液素和蛙皮素对十二指肠溃疡患者五肽胃泌素刺激的胃酸分泌的抑制作用。
Acta Hepatogastroenterol (Stuttg). 1978 Dec;25(6):487-91.
9
Effects of in vivo administration of pentagastrin, secretin, and 13-Nle-Motilin on the in vitro incorporation of 14C-leucine into protein of human gastric mucosa.体内给予五肽胃泌素、促胰液素和13-去甲亮氨酸-胃动素对14C-亮氨酸体外掺入人胃黏膜蛋白质的影响。
Scand J Gastroenterol. 1976;11(7):657-60.
10
Effect of somatostatin, secretin, and glucagon on secretagogue stimulated aminopyrine uptake in isolated canine parietal cells.生长抑素、促胰液素和胰高血糖素对离体犬壁细胞中促分泌素刺激的氨基比林摄取的影响。
Agents Actions. 1983 Jun;13(4):265-8. doi: 10.1007/BF01971476.

引用本文的文献

1
Radionuclide imaging of Meckel's diverticulum: cimetidine versus pentagastrin plus glucagon.梅克尔憩室的放射性核素显像:西咪替丁与五肽胃泌素加胰高血糖素的比较
Eur J Nucl Med. 1984;9(7):316-9. doi: 10.1007/BF00276461.