通过亚胺离子环化反应合成新型嘧啶稠合八元杂环。
Synthesis of novel pyrimidine fused 8-membered heterocycles via iminium ion cyclization reactions.
作者信息
Che Xin, Zheng Lianyou, Dang Qun, Bai Xu
机构信息
The Center for Combinatorial Chemistry and Drug Discovery, Jilin University, 75 Haiwai Street, Changchun, Jilin 130012, PR China.
出版信息
J Org Chem. 2008 Feb 1;73(3):1147-9. doi: 10.1021/jo7020746. Epub 2008 Jan 8.
PMID:18179230
Abstract
Novel tricyclic pyrimidine-fused 8-membered heterocycles were prepared by an iminium ion cyclization using pyrimidinediamine systems with electron-rich aromatic rings.
摘要
通过使用具有富电子芳环的嘧啶二胺体系进行亚胺离子环化反应，制备了新型的三环嘧啶稠合八元杂环化合物。
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