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Macrolide and clindamycin resistance in Staphylococcus aureus isolates and antibiotic use in a Veterans Affairs Medical Center.

作者信息

Modak Rohit, Ross David, Kan Virginia L

机构信息

Infectious Diseases Section, Medical Service, Veterans Affairs Medical Center, Washington, DC 20422, USA.

出版信息

Infect Control Hosp Epidemiol. 2008 Feb;29(2):180-2. doi: 10.1086/526448.

DOI:10.1086/526448
PMID:18179375
Abstract

A retrospective analysis of 13,946 Staphylococcus aureus isolates revealed a stable incidence of isolates that were resistant to both clindamycin and erythromycin, but a significantly increasing incidence of isolates that were susceptible to clindamycin and resistant to erythromycin during 1991-1995, 1996-2000, and 2001-2005. The use of macrolides and clindamycin also increased during 1996-2005. The incidence of S. aureus isolates with inducible clindamycin resistance increased steadily and significantly during the period from August 2004 through December 2005.

摘要

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