Infante Pina D, Badia Llach X, Ariño-Armengol B, Villegas Iglesias V
Unit of Gastroenterology and Nutrition, Children Hospital Vall d'Hebron, Autonomous University, Barcelona, Spain.
World J Gastroenterol. 2008 Jan 14;14(2):248-54. doi: 10.3748/wjg.14.248.
To assess the prevalence of mild gastrointestinal disorders in milk-fed infants in paediatric practice, and to evaluate the effectiveness and satisfaction with dietetic treatment.
A cross-sectional epidemiological study was first carried out. A total of 285 paediatricians included 3487 children seen during a period of one week. In a second phase an observational, prospective and multicentre study was conducted and 2069 milk-fed infants with mild gastrointestinal disorders (colic, constipation, regurgitation and diarrhoea) were included. There was a baseline visit (start of treatment) and a final visit four weeks later. The effectiveness of the various Novalac formulas, as well as the satisfaction of the parents/tutors and paediatricians with the dietetic treatment were assessed at the final visit.
The prevalence of mild gastrointestinal disorders was 27.8% of all paediatrician consultations (9.2%, 7.8%, 6.1% and 4.6% in relation to colic, constipation, regurgitation and diarrhoea, respectively). The several Novalac adapted milk formulas resolved 88.4% of the mild gastrointestinal disorders. Depending on the type of disorder, differences in response rate were observed. The highest effectiveness was recorded with respect to diarrhoea (92.6%), followed by constipation (91.6%), colic (87.6%) and regurgitation (81%). Overall, 91% of the paediatricians and 88.8% of the parents/tutors were satisfied or very satisfied with the Novalac adapted milk formulas.
Mild gastrointestinal disorders show a high prevalence in paediatric practice. The Novalac adapted milk formulas have been shown to be effective in treating mild gastrointestinal disorders in milk-fed infants in the context of routine clinical practice.
评估儿科实践中人工喂养婴儿轻度胃肠功能紊乱的患病率，并评估饮食治疗的有效性及满意度。
首先进行了一项横断面流行病学研究。共有285名儿科医生纳入了在一周内诊治的3487名儿童。在第二阶段，开展了一项观察性、前瞻性多中心研究，纳入了2069名患有轻度胃肠功能紊乱（腹绞痛、便秘、反流和腹泻）的人工喂养婴儿。有一次基线访视（治疗开始时）以及四周后的末次访视。在末次访视时评估了各种诺优能配方奶粉的有效性，以及家长/监护人及儿科医生对饮食治疗的满意度。
轻度胃肠功能紊乱的患病率占所有儿科医生诊疗病例的27.8%（腹绞痛、便秘、反流和腹泻分别占9.2%、7.8%、6.1%和4.6%）。几种诺优能适配奶粉解决了88.4%的轻度胃肠功能紊乱问题。根据紊乱类型观察到了有效率的差异。腹泻的有效率最高（92.6%），其次是便秘（91.6%）、腹绞痛（87.6%）和反流（81%）。总体而言，91%的儿科医生以及88.8%的家长/监护人对诺优能适配奶粉感到满意或非常满意。
轻度胃肠功能紊乱在儿科实践中患病率较高。在常规临床实践中，诺优能适配奶粉已被证明对治疗人工喂养婴儿的轻度胃肠功能紊乱有效。
