Abe T, Furuhashi N, Ohashi I, Suzuki M
Tohoku J Exp Med. 1976 Jun;119(2):197-200. doi: 10.1620/tjem.119.197.
In order to screen the neurotics and non-neurotics of climacteric women with menopausal symptoms, conjugated estrogen was injected intravenously and the reactions were compared. Menopausal symptoms were represented by Kupperman's menopausal index. After estrogen injection the non-neurotics showed a decrease of the index, i.e., alleviation of the symptoms, while the neurotics showed no change of the index. Taking advantage of this difference, a discriminant function between neurotics and non-neurotics was calculated using, as variables, Kupperman's menopasual indices determined before and after administration of the conjugated estrogen. The calculative screening obtained from this discriminant function yielded consistency with clinical diagnosis in about 94% of the neurotics and about 87% of the non-neurotics, suggesting that this test is of value in the screening of neurotics and non-neurotics in the climacteric women with menopausal symptoms.
为了筛查有更年期症状的更年期女性中的神经症患者和非神经症患者，静脉注射结合雌激素并比较反应。更年期症状用库珀曼更年期指数表示。注射雌激素后，非神经症患者指数下降，即症状缓解，而神经症患者指数无变化。利用这种差异，以结合雌激素给药前后测定的库珀曼更年期指数为变量，计算神经症患者和非神经症患者之间的判别函数。从该判别函数获得的计算筛查在约94%的神经症患者和约87%的非神经症患者中与临床诊断一致，表明该测试在筛查有更年期症状的更年期女性中的神经症患者和非神经症患者方面具有价值。
