乳糜微粒血症与乳糜微粒血症综合征：一种实用的管理方法。

Chylomicronemia and the chylomicronemia syndrome: a practical approach to management.

作者信息

Leaf David Alexander

机构信息

Department of Medicine, UCLA School of Medicine, Los Angeles, California, USA.

出版信息

Am J Med. 2008 Jan;121(1):10-2. doi: 10.1016/j.amjmed.2007.10.004.

DOI:10.1016/j.amjmed.2007.10.004

PMID:18187065

Abstract

Chylomicronemia is present when triglyceride levels exceed 1000 mg/dL. Chylomicronemia, when accompanied by eruptive xanthoma, lipemia retinalis, or abdominal symptoms, is referred to as the "chylomicronemia syndrome" and can cause acute pancreatitis. Treatment aimed at reducing triglyceride levels includes lifestyle modifications to promote weight loss with diet and physical activity coupled with medications, including fibrates, n-3 polyunsaturated fatty acids, and nicotinic acid. Chylomicronemic patients with acute pancreatitis require insulinization in an inpatient setting to abolish chylomicronemia.

摘要

当甘油三酯水平超过1000mg/dL时会出现乳糜微粒血症。乳糜微粒血症若伴有疹性黄瘤、视网膜脂血症或腹部症状，则被称为“乳糜微粒血症综合征”，可导致急性胰腺炎。旨在降低甘油三酯水平的治疗方法包括通过饮食和体育活动促进体重减轻的生活方式改变，以及使用药物，包括贝特类药物、n-3多不饱和脂肪酸和烟酸。患有急性胰腺炎的乳糜微粒血症患者需要在住院环境中进行胰岛素治疗以消除乳糜微粒血症。