Pavelić B, Anić I, Najzar-Fleger D, Stilinović B, Temmer K
Stomatoloskog Fakulteta Sveucilista u Zagrebu.
Acta Stomatol Croat. 1991;25(4):207-12.
Calcium hydroxide preparations Ca(OH)2 are used as water solutions, putly, liner, cement or artificial material. The therapeutic effect of each medicaments depends on physical and chemical characteristic of additional components. The aim of the paper is to research the sensitivity of Streptococcus faecalis and Candida albicans to different water solution concentrations of calcium hydroxide. As solid plates, Bacto-Mitis-Salivarius agar was used for S. mutans, Torlak blood agar for S. faecalis and Sabourand agar "Torlak" for C. albicans. The holes were drilled in solid plates and were filled by 0.2 ml of water solutions of Ca(OH)2. Preparations, created as described were incubated aerobically at 37 degrees C in the period of 48 hrs. Results were read after 24 as well as after 48 hrs. The examined solutions of Ca(OH)2, revealed the highest antimicrobic effect after 24 hrs. The result remained unchanged even after 48 hrs. The inhibition of S. mutans growth on the solid plate occurred with the concentration of Ca(OH)2 solution from 271.18 x 10(-2) mol/dm3 and pH 12.76. The growth of S. faecalis at the solid plate was inhibited with the concentration of 3335.21 x 10(-3) mol/dm3 and pH 12.82. The inhibition of C. albicans growth on solid plate occurred with the concentration of Ca(OH)2 solution from 1023.20 x 10(-3) mol/dm3 and pH 12.84. The difference in the sensitivity of the examined microorganisms at the same concentrations of Ca(OH)2 solution was observed.
氢氧化钙制剂Ca(OH)₂ 被用作水溶液、糊剂、衬层、黏固粉或人工材料。每种药物的治疗效果取决于其附加成分的物理和化学特性。本文的目的是研究粪肠球菌和白色念珠菌对不同浓度氢氧化钙水溶液的敏感性。作为固体平板，变形链球菌使用Bacto - Mitis - Salivarius琼脂，粪肠球菌使用Torlak血琼脂，白色念珠菌使用“Torlak”沙氏琼脂。在固体平板上钻孔，并用0.2 ml氢氧化钙水溶液填充。按上述方法制备的制剂在37℃有氧条件下孵育48小时。在24小时和48小时后读取结果。所检测的氢氧化钙溶液在24小时后显示出最高的抗菌效果。即使在48小时后结果仍保持不变。当氢氧化钙溶液浓度为271.18×10⁻² mol/dm³ 且pH值为12.76时，固体平板上变形链球菌的生长受到抑制。当浓度为3335.21×10⁻³ mol/dm³ 且pH值为12.82时，固体平板上粪肠球菌的生长受到抑制。当氢氧化钙溶液浓度为1023.20×10⁻³ mol/dm³ 且pH值为12.84时，固体平板上白色念珠菌的生长受到抑制。观察到在相同浓度的氢氧化钙溶液下，所检测微生物的敏感性存在差异。
