Department of Clinical Pharmacy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Department of Clinical Pharmacy, School of Pharmacy, College of Health and Medical Sciences, Haramaya University, Harar, Ethiopia.
PLoS One. 2021 Aug 26;16(8):e0256195. doi: 10.1371/journal.pone.0256195. eCollection 2021.
Psychiatric patients are at increased risk of being overweight or obese, and subsequently develop metabolic syndrome. Nevertheless, data regarding associated factors for weight gain are limited and inconsistent.
The present study aimed to determine the risk of metabolic syndrome and its associated factors among psychiatric patients.
A cross-sectional quantitative study was conducted among all psychiatric patients at the Psychiatric Unit of the University of Gondar Comprehensive Specialized Hospital from March 1- April 1, 2018. All eligible psychiatric patients were interviewed about their socio-demographic status,and clinical characteristics and useful parameters for the study were recorded from the medical records of the patients and by measuring waist to height ratio. Descriptive statistics were used to summarize baseline information.Binary logistic regression was used to determine the associated factors and P-value <0.05 and confidence interval (CI) of 95% were used as cut off points for determining statistical significance.
From 300 patients included in the study, 168(56%) patients were females,and around 50.3% of the study participants had low literacy levels. As per waist to a height ratio scale, 58% (174) of the patients had a risk of metabolic syndrome. The Binary logistic regression analysis indicated that sex (p-<0.0001), occupation (p -0.032), marital status (p-0.006), and distance from the hospital (p<0.0001) were statistically significant determinants of metabolic syndrome risk in the psychiatric patient in our setting.
The majority of the psychiatric patients in the study setting had a risk of metabolic syndrome. Sex, marital status, employment status, and distance to the hospital were significantly associated with metabolic syndrome. Routine physical and laboratory investigations to detect metabolic syndrome are indispensable in psychiatric patients to prevent cardiovascular complications.
精神科患者超重或肥胖的风险增加，随后会发展为代谢综合征。然而，关于体重增加相关因素的数据有限且不一致。
本研究旨在确定精神科患者发生代谢综合征的风险及其相关因素。
2018 年 3 月 1 日至 4 月 1 日，在贡德尔大学综合专科医院的精神科病房对所有精神科患者进行了一项横断面定量研究。所有符合条件的精神科患者均接受了社会人口统计学状况和临床特征的访谈，并从患者的病历中记录了对本研究有用的参数以及通过测量腰高比进行了记录。使用描述性统计对基线信息进行了总结。使用二项逻辑回归来确定相关因素，以 P 值<0.05 和 95%置信区间（CI）为 0.05 作为确定统计学意义的截止值。
在纳入研究的 300 名患者中，有 168 名（56%）患者为女性，大约有 50.3%的研究参与者文化程度较低。根据腰高比量表，58%（174 名）患者有发生代谢综合征的风险。二项逻辑回归分析表明，性别（p<0.0001）、职业（p-0.032）、婚姻状况（p-0.006）和距医院的距离（p<0.0001）是本研究中精神科患者发生代谢综合征风险的统计学显著决定因素。
在研究环境中，大多数精神科患者有发生代谢综合征的风险。性别、婚姻状况、就业状况和距医院的距离与代谢综合征显著相关。对精神科患者进行常规的体格检查和实验室检查以检测代谢综合征是必不可少的，可预防心血管并发症。
