Tarrant Janice, Severson Holly, Wildsoet Christine F
School of Optometry, 592 Minor Hall, University of California, Berkeley, CA 94720-2020, USA.
Ophthalmic Physiol Opt. 2008 Jan;28(1):62-72. doi: 10.1111/j.1475-1313.2007.00529.x.
To assess the effect of bifocal soft contact lenses on the accommodative errors (lags) of young adults. Recent studies suggest that bifocal soft contact lenses are an effective myopia control treatment although the underlying mechanism is not understood.
Accommodation responses were measured for four target distances: 100, 50, 33 and 25 cm in 35 young adult subjects (10 emmetropes and 25 myopes; mean age, 22.8 +/- 2.5 years). Measurements were made under both monocular and binocular conditions with three types of lenses: single vision distance soft contact lenses (SVD), single vision near soft contact lenses (SVN; +1.50 D added to the distance prescription) and bifocal soft contact lenses (BF; +1.50 D add).
For the SVD lenses, all subjects exhibited lags of accommodation, with myopes accommodating significantly less than emmetropes for the 100 and 50 cm target distances (p < 0.05). With the SVN lenses, there was no significant difference in accommodative responses between emmetropes and myopes. With the BF lenses, both emmetropic and myopic groups exhibited leads in accommodation for all target distances, with emmetropes showing significantly greater leads for all distances (p < 0.005).
Overall, myopes tended to accommodate less than emmetropes, irrespective of the contact lens type, which significantly affected accommodation for both groups. The apparent over-accommodation of myopes when wearing the BF contact lenses may explain the reported efficacy as a myopia control treatment, although further studies are required to elucidate the mechanism underlying this accommodative effect.
评估双焦点软性隐形眼镜对年轻成年人调节误差(滞后)的影响。近期研究表明,双焦点软性隐形眼镜是一种有效的近视控制治疗方法,尽管其潜在机制尚不清楚。
对35名年轻成年受试者(10名正视者和25名近视者;平均年龄22.8±2.5岁)在四个目标距离(100、50、33和25厘米)下测量调节反应。在单眼和双眼条件下使用三种类型的镜片进行测量:单视远用软性隐形眼镜(SVD)、单视近用软性隐形眼镜(SVN;在远用处方上加+1.50 D)和双焦点软性隐形眼镜(BF;加+1.50 D)。
对于SVD镜片,所有受试者均表现出调节滞后,在100和50厘米目标距离下,近视者的调节明显少于正视者(p<0.05)。佩戴SVN镜片时,正视者和近视者的调节反应无显著差异。佩戴BF镜片时,正视组和近视组在所有目标距离下均表现出调节超前,正视者在所有距离下的调节超前均显著更大(p<0.005)。
总体而言,无论隐形眼镜类型如何,近视者的调节往往少于正视者,这对两组的调节均有显著影响。近视者佩戴BF隐形眼镜时明显的过度调节可能解释了其作为近视控制治疗方法所报道的疗效,尽管需要进一步研究以阐明这种调节作用的潜在机制。