Povey S, Slaughter C A, Wilson D E, Gormley I P, Buckton K E, Perry P, Bobrow M
Ann Hum Genet. 1976 May;39(4):413-22. doi: 10.1111/j.1469-1809.1976.tb00145.x.
The segregation of human enzymes and chromosomes has been studied in more than 30 independent primary human-rodent somatic cell hybrids and a series of 64 subclones. The results strongly suggest that the locus determining AK1, 'red cell' adenylate kinase, is on chromosome 9 in man, and hence that the locus for the ABO blood groups and that for the Nail-patella syndrome may also be assigned to this chromosome. Evidence is presented indicating that another adenylate kinase, nucleoside triphosphate adenylate kinase, and also the soluble form of aconitase, are probably syntenic with AK1, and that the mitochondrial form of aconitase is probably not syntenic with these loci.
在30多个独立的人-啮齿动物体细胞杂交原代细胞以及一系列64个亚克隆中，对人类酶和染色体的分离进行了研究。结果有力地表明，决定“红细胞”腺苷酸激酶AK1的基因座位于人类的9号染色体上，因此ABO血型基因座和指甲-髌骨综合征基因座也可能定位于该染色体。有证据表明，另一种腺苷酸激酶，即核苷三磷酸腺苷酸激酶，以及乌头酸酶的可溶性形式，可能与AK1同线，而乌头酸酶的线粒体形式可能与这些基因座不同线。
