Scarpelli Ana C, Paiva Saul M, Pordeus Isabela A, Ramos-Jorge Maria L, Varni James W, Allison Paul J
Department of Pediatric Dentistry and Orthodontics, Faculty of Dentistry, Federal University of Minas Gerais - Av, Antônio Carlos 6627, Belo Horizonte, MG, 31270-901, Brazil.
Health Qual Life Outcomes. 2008 Jan 22;6:7. doi: 10.1186/1477-7525-6-7.
The use of health-related quality of life (HRQOL) measurements has been increased progressively in health surveys. These measurements document the functional and psychosocial outcomes of health conditions and complement clinical indicators to provide a comprehensive description of individuals and populations' health. The Pediatric Quality of Life Inventory (PedsQL) is a promising instrument with age-appropriate versions. The objective of the current paper was to evaluate the psychometric properties of the PedsQL 3.0 Cancer Module cross-culturally adapted for use in Brazil.
A cross-sectional study was developed with 190 Brazilian families of individuals from 2 to 18 years of age, of both genders, with cancer in various phases of treatment or control. Subjects were recruited by means of convenience samples from the Pediatric Hematology/Oncology Centers at two public hospitals. 'In-treatment' status was defined as individuals who were receiving medical care to induce remission. 'Off-treatment' status was defined as individuals for whom all therapy was completed for a period of at least one month. Reliability was determined through test-retest reliability and internal consistency. The validity of the Cancer Module was determined through discriminant and convergent validity. Correlations between the scores obtained by the children/adolescents with cancer and their guardians were assessed.
Test-retest reliability demonstrated good correlation (0.69-0.90 for children/adolescents; 0.71-0.93 for guardians) and adequate agreement of the items (0.26-0.85 for children/adolescents; 0.25-0.87 for guardians). Internal consistency demonstrated adequate indices in comparisons between groups (alpha = 0.78-0.80 for children and adolescents; 0.68-0.88 for guardians). The 'pain and hurt', 'nausea', 'procedural anxiety' and 'treatment anxiety' subscales proved capable of distinguishing the groups of children in treatment and off treatment (p < 0.05). Positive significant correlations were observed between the scores of the PedsQL 3.0 Cancer Module and the PedsQL 4.0 Generic Core scales. Weak correlations were found between the reports of the children and those of the guardians.
The Brazilian version of the PedsQL 3.0 Cancer Module exhibited good measurement properties regarding reproducibility and construct validity.
在健康调查中，与健康相关的生活质量（HRQOL）测量的使用已逐渐增加。这些测量记录了健康状况的功能和心理社会结果，并补充临床指标以全面描述个人和人群的健康状况。儿童生活质量量表（PedsQL）是一种很有前景的工具，有适合不同年龄段的版本。本文的目的是评估跨文化改编后适用于巴西的PedsQL 3.0癌症模块的心理测量特性。
开展了一项横断面研究，研究对象为190个巴西家庭，家庭成员为2至18岁的男女儿童，处于癌症治疗或控制的不同阶段。通过便利抽样从两家公立医院的儿科血液学/肿瘤学中心招募受试者。“治疗中”状态定义为正在接受诱导缓解医疗护理的个体。“治疗后”状态定义为所有治疗已完成至少一个月的个体。通过重测信度和内部一致性来确定信度。通过判别效度和聚合效度来确定癌症模块的效度。评估了患癌症的儿童/青少年及其监护人获得的分数之间的相关性。
重测信度显示出良好的相关性（儿童/青少年为0.69 - 0.90；监护人为0.71 - 0.93），且各项目的一致性良好（儿童/青少年为0.26 - 0.85；监护人为0.25 - 0.87）。内部一致性在组间比较中显示出足够的指标（儿童和青少年的α系数为0.78 - 0.80；监护人的α系数为0.68 - 0.88）。“疼痛与伤害”、“恶心”、“治疗程序焦虑”和“治疗焦虑”子量表能够区分治疗中和治疗后的儿童组（p < 0.05）。在PedsQL 3.0癌症模块的分数与PedsQL 4.0通用核心量表的分数之间观察到显著的正相关。儿童与监护人的报告之间发现弱相关性。
巴西版的PedsQL 3.0癌症模块在可重复性和结构效度方面表现出良好的测量特性。
