肝细胞癌患者的副肿瘤性黑棘皮病类型。

Paraneoplastic type of acanthosis nigricans in patient with hepatocellular carcinoma.

作者信息

Kamińska-Winciorek G, Brzezińska-Wcisło L, Lis-Swiety A, Krauze E

机构信息

Dermatological Department of Silesian University of Medicine, Katowice, Poland.

出版信息

Adv Med Sci. 2007;52:254-6.

PMID:18217428

Abstract

UNLABELLED

Paraneoplastic acanthosis nigricans is connected with malignancies in adults in almost 100% of cases. The typical skin changes include: thickening and hyperpigmentation in typical localization with mucocutaneous involvement.

PURPOSE

The authors report a case of a malignant type of acanthosis nigricans in 42-year-old female patient with hepatocellular carcinoma.

CASE REPORT

First skin lesions appeared in 2000. The patient died within 22 months (of the first appearance of skin symptoms), because of hepatocellular carcinoma. Herein we report the clinical picture, skin involvement and diagnostic procedures in acanthosis nigricans.

CONCLUSIONS

Paraneoplastic type of acanthosis nigricans--in patient with hepatocellular carcinoma is not frequently reported in the literature. In the aspect of clinical occurrence of skin lesions suggesting acanthosis nigricans the diagnostics should be focused on internal malignancies.

摘要