Richardson Lisa C, Wingo Phyllis A, Zack Matthew M, Zahran Hatice S, King Jessica B
Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.
Cancer. 2008 Mar 15;112(6):1380-9. doi: 10.1002/cncr.23291.
The authors examined the health-related quality of life (HRQOL) of cancer survivors between ages 20 and 64 years by using a population-based survey of individuals who had activity limitations caused by cancer.
A population-based, cross-sectional study was conducted using the 2000 to 2002 Centers for Disease Control and Prevention (CDC) Behavioral Risk Factor Surveillance System (BRFSS) to examine HRQOL among respondents who reported activity limitations because of cancer. HRQOL was measured by using the CDC's Healthy Days Measures, including self-rated health status, numbers of unhealthy physical and mental health days, and activity limitation. HRQOL was compared among the following groups: those who reported no activity limitations and those who were limited primarily by cardiovascular conditions, emotional problems, and cancer. Taylor-series linearization methods were used to calculate population-based estimates in this complex sample survey.
Individuals between ages 20 and 64 years who were limited by cancer reported poorer HRQOL measured as higher prevalence of poor or fair self-reported health, more physically unhealthy days, more painful days, and more inadequate sleep days. Compared with the group that had no activity limitations, the individuals who had limitations were more likely to be women and to have annual household incomes<$25,000. They were more likely to be unable to work and to have health insurance. In addition, they were more likely to be former smokers and to be overweight, but they were less likely to participate in leisure-time physical activity.
Overall, respondents between ages 20 and 64 years who reported being limited primarily by cancer reported lower HRQOL. They also reported unhealthy behaviors that were detrimental to improved HRQOL. The HRQOL and lifestyle modification needs of this population need to be examined prospectively to help decrease their burden of suffering.
作者通过对因癌症导致活动受限的个体进行基于人群的调查,研究了20至64岁癌症幸存者的健康相关生活质量(HRQOL)。
利用2000年至2002年疾病控制与预防中心(CDC)行为危险因素监测系统(BRFSS)进行了一项基于人群的横断面研究,以调查报告因癌症导致活动受限的受访者的HRQOL。HRQOL通过使用CDC的健康日测量方法进行测量,包括自我评估的健康状况、不健康的身体和心理健康天数以及活动受限情况。在以下几组人群中比较了HRQOL:报告无活动受限的人群以及主要受心血管疾病、情绪问题和癌症限制的人群。在这个复杂的样本调查中,使用泰勒级数线性化方法来计算基于人群的估计值。
年龄在20至64岁之间因癌症而活动受限的个体报告的HRQOL较差,表现为自我报告健康状况差或一般的患病率较高、身体不健康天数更多、疼痛天数更多以及睡眠不足天数更多。与无活动受限的人群相比,有活动受限的个体更可能是女性,家庭年收入<$25,000。他们更可能无法工作且没有健康保险。此外,他们更可能是曾经吸烟者且超重,但参与休闲体育活动的可能性较小。
总体而言,报告主要受癌症限制的20至64岁受访者的HRQOL较低。他们还报告了不利于改善HRQOL的不健康行为。需要对这一人群的HRQOL和生活方式改变需求进行前瞻性研究,以帮助减轻他们的痛苦负担。