急性心肌缺血和再灌注期间n-酪醇的抗心律失常活性。
Antiarrhythmic activity of n-tyrosol during acute myocardial ischemia and reperfusion.
作者信息
Chernyshova G A, Plotnikov M B, Smol'yakova V I, Golubeva I V, Aliev O I, Tolstikova T G, Krysin A P, Sorokina I V
机构信息
Department of Circulation Pharmacology, State Research Institute of Pharmacology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences.
出版信息
Bull Exp Biol Med. 2007 Jun;143(6):689-91. doi: 10.1007/s10517-007-0215-7.
Antiarrhythmic activity of n-tyrosol was demonstrated on the model of early occlusion and reperfusion arrhythmia. The preparation reduces the incidence of ventricular tachycardia and fibrillation, increases the percent of animals without ventricular arrhythmia, and moderates the severity of developing ventricular arrhythmias.
在早期闭塞和再灌注心律失常模型上证实了对香豆醇的抗心律失常活性。该制剂降低了室性心动过速和颤动的发生率，增加了无室性心律失常动物的百分比，并减轻了室性心律失常发展的严重程度。
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