Luo Betsy P, Brown Gary C, Luo Solomon C, Brown Melissa M
Center for Value-Based Medicine, Flourtown, Pennsylvania 19031, USA.
Am J Ophthalmol. 2008 Apr;145(4):618-622. doi: 10.1016/j.ajo.2007.12.011. Epub 2008 Feb 19.
To determine the health-related quality of life associated with the presbyopia.
Cross-sectional, patient preference-based, time trade-off utility analysis.
One hundred and ten patients with spectacle-corrected presbyopia and a best-corrected visual acuity of 20/40 or better were interviewed in a cross-sectional fashion using a standardized, validated, time trade-off utility analysis questionnaire.
The mean utility associated with the health state of presbyopia in our sample was 0.980 (standard deviation, 0.086; 95% confidence interval, 0.964 to 0.996). Ten percent of the cohort had a presbyopia-associated utility of 0.95 or less. Age, gender, level of education, marital status, and the degree of presbyopia did not significantly affect the time trade-off utilities associated with presbyopia.
Presbyopia corrected with glasses is associated with a nominal decrease in quality of life, similar to that of treated hypertension, for the average person with the condition. Approximately 10% of such patients theoretically may be candidates for an intervention other than spectacles to correct the condition.
确定与老花眼相关的健康相关生活质量。
横断面研究，基于患者偏好的时间权衡效用分析。
采用标准化、经过验证的时间权衡效用分析问卷，以横断面方式对110例佩戴眼镜矫正老花眼且最佳矫正视力为20/40或更好的患者进行访谈。
在我们的样本中，与老花眼健康状态相关的平均效用为0.980（标准差为0.086；95%置信区间为0.964至0.996）。该队列中有10%的患者与老花眼相关的效用为0.95或更低。年龄、性别、教育程度、婚姻状况和老花眼程度并未显著影响与老花眼相关的时间权衡效用。
对于患有老花眼的普通人，佩戴眼镜矫正的老花眼与生活质量的名义下降相关，类似于治疗后的高血压。理论上，约10%的此类患者可能是除眼镜矫正之外的其他干预措施的候选者。
