Demirel Fuat, Cakan Murat, Yalçinkaya Fatih, Topcuoglu Murat, Altug Ugur
Department of Urology, SB Ankara Diskapi Training Hospital, Ankara 06800, Turkey.
Int Urol Nephrol. 2008;40(3):643-7. doi: 10.1007/s11255-008-9331-1. Epub 2008 Feb 5.
In this study, we analyzed the effect of Turkish coffee and black tea consumption, alcohol intake and smoking on bladder cancer.
A total of 164 patients with bladder tumors and 324 individuals without primary tumors were included in the study. The habits of coffee and tea consumption, alcohol intake and smoking were queried.
No association was found between bladder cancer and drinking coffee (p=0.89) and tea (p=0.37), but alcohol intake was found to be associated, with an odds ratio (OR) of 1.85 (95% CI 1.15-2.96; p=0.009). While there was a relationship between bladder cancer and smoking and quitting smoking (OR: 4.84 [95% CI 2.93-8.00; p<0.001] and OR: 4.10 [95% CI 2.41-6.97; p<0.001] respectively), the associations between bladder cancer and smoking and quitting smoking were similar (OR: 1.18, 95% CI 0.74-1.86; p=0.477). Smoking<10 cigarettes a day created an OR of 2.14 (95% CI 1.11-4.12; p<0.001); 10-20 cigarettes an OR of 4.50 (95% CI 2.74-7.37; p<0.001); >20 cigarettes an OR of 14.85 (95% CI 6.83-32.27; p<0.001); smoking by inhaling the smoke an OR of 4.72 (95% CI 2.94-7.59; p<0.001), and smoking by not inhaling the smoke an OR of 3.34 (95% CI 1.75-6.38; p<0.001). The associations between bladder cancer and inhaling smoke and not inhaling smoke were similar (OR: 1.41, 95% CI 0.85-2.48; p=0.228).
We found that smoking and alcohol consumption are closely connected with bladder cancer. Our data showed that not inhaling the smoke was as much associated with bladder cancer as inhaling the smoke. The association between smoking and bladder cancer lasts after quitting smoking.
在本研究中，我们分析了饮用土耳其咖啡和红茶、饮酒及吸烟对膀胱癌的影响。
本研究共纳入164例膀胱肿瘤患者和324例无原发性肿瘤的个体。询问了咖啡和茶的饮用习惯、饮酒及吸烟情况。
未发现膀胱癌与喝咖啡（p = 0.89）和喝茶（p = 0.37）之间存在关联，但发现饮酒与之有关联，比值比（OR）为1.85（95%置信区间1.15 - 2.96；p = 0.009）。虽然膀胱癌与吸烟及戒烟之间存在关联（OR分别为4.84 [95%置信区间2.93 - 8.00；p < 0.001]和4.10 [95%置信区间2.41 - 6.97；p < 0.001]），但膀胱癌与吸烟及戒烟之间的关联相似（OR：1.18，95%置信区间0.74 - 1.86；p = 0.477）。每天吸烟<10支的OR为2.14（95%置信区间1.11 - 4.12；p < 0.001）；10 - 20支的OR为4.50（95%置信区间2.74 - 7.37；p < 0.001）；>20支的OR为14.85（95%置信区间6.83 - 32.27；p < 0.001）；吸入烟雾吸烟的OR为4.72（95%置信区间2.94 - 7.59；p < 0.001），不吸入烟雾吸烟的OR为3.34（95%置信区间1.75 - 6.38；p < 0.001）。膀胱癌与吸入烟雾和不吸入烟雾之间的关联相似（OR：1.41，95%置信区间0.85 - 2.48；p = 0.228）。
我们发现吸烟和饮酒与膀胱癌密切相关。我们的数据表明，不吸入烟雾与吸入烟雾一样与膀胱癌有关。戒烟后吸烟与膀胱癌之间的关联依然存在。
