Li Xiao-zhong, Tong Mu-er, Ou La, Zhang Ran, Rong Liao-jiang, Hou Qiao-fang, Yu Bin, Li Sheng-bin
People's Procuratorate of Inner Mongolia Autonomous Region, Hohhot, People's Republic of China.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2008 Feb;25(1):89-92.
To investigate the genetic structure of X chromosome in Mongolia, Ewenki, Elunchun and Dawoer in Inner Mongolia.
Nine short tandem repeat (STR) markers on the X chromosome (DXS6789, DXS101, DXS8378, DXS7132, DXS7133, DXS7423, DXS6804, DXS6799 and HPRTB) were analyzed in the four populations from Inner Mongolian (Mongol, Ewenki,Oroqen and Daur) for their genetic diversity, forensic suitability and possible genetic affinities of the populations. Frequencies and other parameters of forensic interest were computed.
The results revealed that the nine markers described here have a moderate degree of variability in the population groups. And there are significant differences in the genetic variability among the populations. Genetic distance and cluster analyses show very low genetic distance between Mongol and Han (Xi'an) communities. The results based on genetic distance analyses are consistent with earlier studies based on linguistic as well as immigration history and origin of these populations.
The nine STR loci studied here were found not only useful in studying genetic variations between populations but also suitable for human identity testing.
研究内蒙古蒙古族、鄂温克族、鄂伦春族和达斡尔族的X染色体遗传结构。
对内蒙古的四个群体（蒙古族、鄂温克族、鄂伦春族和达斡尔族）的9个X染色体短串联重复序列（STR）标记（DXS6789、DXS101、DXS8378、DXS7132、DXS7133、DXS7423、DXS6804、DXS6799和HPRTB）进行分析，以了解其遗传多样性、法医学适用性以及群体间可能的遗传亲缘关系。计算了法医学相关的频率和其他参数。
结果显示，这里描述的9个标记在各群体中有中等程度的变异性。群体间的遗传变异性存在显著差异。遗传距离和聚类分析表明蒙古族和汉族（西安）群体之间的遗传距离非常低。基于遗传距离分析的结果与早期基于语言以及这些群体的移民历史和起源的研究结果一致。
研究发现，这里所研究的9个STR位点不仅有助于研究群体间的遗传变异，而且适用于个体识别检测。
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