Kandogan Tolga, Erkan Nazif, Vardar Enver
Department of Otolaryngology, Izmir Training and Research Hospital, Bozyaka, Izmir, Turkey.
J Med Case Rep. 2008 Feb 8;2:42. doi: 10.1186/1752-1947-2-42.
This is a case report of a 44-year-old woman with papillary carcinoma of a thyroglossal duct cyst.
A 44 year-old woman presented to the otolaryngology outpatient clinic with an asymptomatic anterior midline neck mass. A cervical ultrasound showed a lesion which appeared to be a thyroglossal duct cyst and surgical resection using Sistrunk's procedure was performed. The histopathologic diagnosis showed papillary carcinoma evolving from a thyroglossal duct cyst, confined to the thyroglossal cyst, with a tumor diameter of 2 cm. The patient then underwent total thyroidectomy and bilateral neck dissection. The final pathology reported an 8 mm papillary cancer in the left lobe of the thyroid without any metastasis to the cervical lymph nodes. The patient was treated with radioactive iodide and thyroid suppresion therapy was given as adjuvant treatment. The patient has been following for two years without any metastasis.
Malignancy within a thyroglossal duct cyst is very rare but should be considered in the differential diagnosis of a midline neck mass.
本文报告一例44岁女性甲状腺舌管囊肿乳头状癌病例。
一名44岁女性因无症状的颈部前正中肿块就诊于耳鼻喉科门诊。颈部超声显示一个似乎是甲状腺舌管囊肿的病变，并采用Sistrunk手术进行了手术切除。组织病理学诊断显示为起源于甲状腺舌管囊肿的乳头状癌，局限于甲状腺舌管囊肿内，肿瘤直径为2厘米。患者随后接受了甲状腺全切除术和双侧颈部清扫术。最终病理报告显示甲状腺左叶有一个8毫米的乳头状癌，无颈部淋巴结转移。患者接受了放射性碘治疗，并给予甲状腺抑制治疗作为辅助治疗。患者已随访两年，无任何转移。
甲状腺舌管囊肿内的恶性肿瘤非常罕见，但在中线颈部肿块的鉴别诊断中应予以考虑。
