Kwan W B, Liu F F, Banerjee D, Rotstein L E, Tsang R W
Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Ont.
Can J Surg. 1996 Aug;39(4):328-32.
Carcinomas of thyroglossal duct cysts are rare. Most are papillary carcinomas; only about 5% are squamous cell carcinomas. Only one case of mixed papillary and squamous cell carcinoma of a thyroglossal duct cyst has been reported so far. The authors present a second case, that of a 38-year-old man who was first seen with a midline neck lump. It was diagnosed clinically as a thyroglossal duct cyst and was locally excised. Pathological examination showed both a concurrent papillary carcinoma and a squamous cell carcinoma. Treatment consisted of a near-total thyroidectomy, ablative radioactive iodine and adjuvant external radiation therapy. The authors review the literature and explain the rationale behind their choice of treatment.
甲状舌管囊肿癌很罕见。大多数是乳头状癌；只有约5%是鳞状细胞癌。到目前为止，仅报道过1例甲状舌管囊肿的混合性乳头状和鳞状细胞癌。作者报告了第2例，是一名38岁男性，最初因颈部中线肿块就诊。临床诊断为甲状舌管囊肿并进行了局部切除。病理检查显示同时存在乳头状癌和鳞状细胞癌。治疗包括近全甲状腺切除术、放射性碘消融和辅助性外照射放疗。作者回顾了文献并解释了他们选择治疗方法的依据。
