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坦桑尼亚北部农村高地孕产妇死亡的危险因素:一项病例对照研究。

Risk factors for maternal death in the highlands of rural northern Tanzania: a case-control study.

作者信息

Evjen-Olsen Bjørg, Hinderaker Sven Gudmund, Lie Rolv Terje, Bergsjø Per, Gasheka Peter, Kvåle Gunnar

机构信息

Haydom Lutheran Hospital, Mbulu District, Manyara Region, Tanzania.

出版信息

BMC Public Health. 2008 Feb 8;8:52. doi: 10.1186/1471-2458-8-52.

Abstract

BACKGROUND

Tanzania has one of the highest maternal mortality ratios in sub-Saharan Africa. Due to the paucity of epidemiological information on maternal deaths, and the high maternal mortality estimates found earlier in the study area, our objective was to assess determinants of maternal deaths in a rural setting in the highlands of northern Tanzania by comparing the women dying of maternal causes with women from the same population who had attended antenatal clinics in the same time period.

METHODS

A case-control study was done in two administrative divisions in Mbulu and Hanang districts in rural Tanzania. Forty-five cases of maternal death were found through a comprehensive community- and health-facility based study in 1995 and 1996, while 135 antenatal attendees from four antenatal clinics in the same population, geographical area, and time-span of 1995-96 served as controls. The cases and controls were compared using multivariate logistic regression analyses. Odds ratios, with 95% confidence intervals, were used as an approximation of relative risk, and were adjusted for place of residence (ward) and age. Further adjustment was done for potentially confounding variables.

RESULTS

An increased risk of maternal deaths was found for women from 35-49 years versus 15-24 years (OR 4.0; 95%CI 1.5-10.6). Women from ethnic groups other than the two indigenous groups of the area had an increased risk of maternal death (OR 13.6; 95%CI 2.5-75.0). There was an increased risk when women or husbands adhered to traditional beliefs, (OR 2.1; 95%CI 1.0-4.5) and (OR 2.6; 95%CI 1.2-5.7), respectively. Women whose husbands did not have any formal education appeared to have an increased risk (OR 2.2; 95%CI 1.0-5.0).

CONCLUSION

Increasing maternal age, ethnic and religious affiliation, and low formal education of the husbands were associated with increased risk of maternal death. Increased attention needs to be given to formal education of both men and women. In addition, education of the male decision-makers should be given high priority in the community, especially in matters concerning pregnancy and delivery preparedness, since their choice greatly affects the survival of the pregnant and delivering women.

摘要

背景

坦桑尼亚是撒哈拉以南非洲孕产妇死亡率最高的国家之一。由于缺乏关于孕产妇死亡的流行病学信息,且研究区域早期的孕产妇死亡率估计较高,我们的目标是通过比较在坦桑尼亚北部高地农村地区因孕产妇原因死亡的妇女与同期在同一人群中参加过产前诊所的妇女,来评估孕产妇死亡的决定因素。

方法

在坦桑尼亚农村的姆布卢和哈南格区的两个行政区开展了一项病例对照研究。通过1995年和1996年基于社区和卫生设施的全面研究发现了45例孕产妇死亡病例,而在1995 - 1996年同一人群、地理区域和时间段内,来自四个产前诊所的135名产前就诊者作为对照。使用多变量逻辑回归分析对病例和对照进行比较。比值比及其95%置信区间被用作相对风险的近似值,并根据居住地点(病房)和年龄进行了调整。对潜在的混杂变量进行了进一步调整。

结果

发现35 - 49岁的女性与15 - 24岁的女性相比,孕产妇死亡风险增加(比值比4.0;95%置信区间1.5 - 10.6)。该地区两个本土族群以外的其他族群的女性孕产妇死亡风险增加(比值比13.6;95%置信区间2.5 - 75.0)。当女性或其丈夫坚持传统信仰时,风险增加,分别为(比值比2.1;95%置信区间1.0 - 4.5)和(比值比2.6;95%置信区间1.2 - 5.7)。丈夫没有接受过任何正规教育的女性似乎风险增加(比值比2.2;95%置信区间1.0 - 5.0)。

结论

孕产妇年龄增加、族群和宗教归属以及丈夫正规教育程度低与孕产妇死亡风险增加有关。需要更加关注男性和女性的正规教育。此外,在社区中应高度重视对男性决策者的教育,特别是在与怀孕和分娩准备相关的问题上,因为他们的选择对孕妇和分娩妇女的生存有很大影响。

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