Tornow R P, Beuel S, Zrenner E
Appl Opt. 1997 Aug 1;36(22):5621-9. doi: 10.1364/ao.36.005621.
The necessary modifications and technical requirements are described for using a commercially available scanning laser ophthalmoscope (Rodenstock Model 101 SLO) as an imaging densitometer to assess human photopigment distribution. The main requirements are a linear detector amplifier, fast shutters for the laser beams, and a trigger unit. Images must be compensated for varying laser intensity. Both rod and cone photopigments are measured with the 514-nm argon laser of the SLO. Discrimination is possible owing to the different spatial distribution. The cone pigment density peaks in the foveal center (D = 0.40) with a steep decrease with increasing eccentricity E (full width at half-maximum, 2.5 degrees ). Rod photopigment increases with increasing eccentricity (D = 0.23 for E = 11 degrees ). These values are in agreement with previous reported results obtained with scanning laser ophthalmoscopes specially designed for retinal densitometry and high stability.
描述了使用市售扫描激光检眼镜(Rodenstock 101型SLO)作为成像密度计来评估人类光色素分布所需的修改和技术要求。主要要求是线性探测器放大器、用于激光束的快速快门和触发单元。必须对图像进行补偿以校正变化的激光强度。使用SLO的514纳米氩激光测量视杆和视锥光色素。由于不同的空间分布,可以进行区分。视锥色素密度在中央凹中心达到峰值(D = 0.40),随着偏心度E增加而急剧下降(半高宽为2.5度)。视杆光色素随偏心度增加而增加(对于E = 11度,D = 0.23)。这些值与先前使用专门为视网膜密度测定设计的具有高稳定性的扫描激光检眼镜所报告的结果一致。