Institute of Ophthalmology, London, UK.
Invest Ophthalmol Vis Sci. 2010 Aug;51(8):4346-50. doi: 10.1167/iovs.09-4556. Epub 2010 Mar 24.
Impaired fixation stability is associated with reduced reading speed. In previous research, fixation stability has been assessed using an infrared eye tracker or a confocal scanning laser ophthalmoscope. The new MP-1 microperimeter from Nidek Technologies (Padova, Italy) provides another option for the assessment of fixation. Here the authors compare fixation stability values measured using the MP-1 microperimeter and the Rodenstock scanning laser ophthalmoscope (SLO; Rodenstock GmbH, Munich, Germany) in persons with and without diabetic maculopathy.
Sixteen normally sighted volunteers and 21 patients with diabetic maculopathy were recruited. Fixation stability was recorded monocularly on the SLO and the MP-1 in counterbalanced order while participants fixated a red 1 degree cross. Fixation data collected from each instrument were used to calculate a bivariate contour ellipse area (BCEA) that encompassed 68% of fixation points.
For control subjects, MP-1 BCEA values were larger than SLO by 0.25 log min arc(2), though the difference was small (10%) and of borderline significance (MP-1, 2.51 log min arc(2); SLO, 2.26 log min arc(2); P = 0.06). In patients with diabetic maculopathy there was no significant difference between MP-1 and SLO values (MP-1, 2.94 log min arc(2); SLO, 2.90 log min arc(2); P = 0.88).
No significant difference was found in BCEA values from the SLO and MP-1 in control subjects and patients with diabetic maculopathy. The authors suggest that the similarity between BCEA values, together with the consistent and reliable operation of the MP-1, make it a useful and viable alternative to the SLO in the assessment of fixation.
固视稳定性受损与阅读速度下降有关。在之前的研究中,使用红外眼动追踪仪或共焦扫描激光检眼镜评估固视稳定性。来自日本尼德克株式会社(意大利帕多瓦)的新型 MP-1 微视野计为评估固视提供了另一种选择。本文作者比较了正常视力者和糖尿病性黄斑病变患者使用 MP-1 微视野计和 Rodenstock 扫描激光检眼镜(Rodenstock GmbH,德国慕尼黑)测量的固视稳定性值。
招募了 16 名正常视力志愿者和 21 名糖尿病性黄斑病变患者。参与者在单眼注视红色 1 度十字时,在 Rodenstock 扫描激光检眼镜和 MP-1 上以平衡顺序记录固视稳定性。从每个仪器收集的固视数据用于计算双变量轮廓椭圆面积(BCEA),该面积包含 68%的固视点。
对于对照组,MP-1 的 BCEA 值比 Rodenstock 扫描激光检眼镜大 0.25 log min arc(2),尽管差异较小(10%),但具有边界意义(MP-1,2.51 log min arc(2);Rodenstock 扫描激光检眼镜,2.26 log min arc(2);P = 0.06)。在糖尿病性黄斑病变患者中,MP-1 和 Rodenstock 扫描激光检眼镜的值之间无显著差异(MP-1,2.94 log min arc(2);Rodenstock 扫描激光检眼镜,2.90 log min arc(2);P = 0.88)。
在对照组和糖尿病性黄斑病变患者中,Rodenstock 扫描激光检眼镜和 MP-1 的 BCEA 值无显著差异。作者认为,BCEA 值的相似性以及 MP-1 的一致和可靠操作,使其成为评估固视的一种有用且可行的替代方法。