May Christian-Albrecht, Narfström Kristina
Department of Anatomy, Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany.
Exp Eye Res. 2008 Mar;86(3):537-40. doi: 10.1016/j.exer.2007.12.011. Epub 2008 Jan 9.
Blood flow in the choroid of eyes with retinal degeneration is normally reduced. In the Abyssinian cat, where no changes in choroidal blood flow were observed recently, a closer morphological analysis revealed that two factors might have lead to this finding. (a) The cat's eye consists of a tapetum lucidum where 15.5 microm microspheres cannot reach the precapillary branching in contrast to the non-tapetal areas, where microspheres were located right next to the choriocapillaris. This fact has not yet been described and might be important for further physiological measurements in eyes of species with a tapetum lucidum. (b) The tapetal cells themselves might have a protective role for the choriocapillaris and RPE during retinal degeneration in this specific animal model. Even in late stages of retinal degeneration the RPE and choriocapillaris in areas covered by the tapetum lucidum were not affected whereas non-tapetal areas showed loss of RPE and capillaries.
患有视网膜变性的眼睛脉络膜中的血流量通常会减少。在阿比西尼亚猫中，最近未观察到脉络膜血流量的变化，但更仔细的形态学分析表明，有两个因素可能导致了这一发现。(a) 猫眼有一层明毯，与无微毯区域相比，15.5微米的微球无法到达毛细血管前分支，在无微毯区域，微球紧邻脉络膜毛细血管。这一事实尚未被描述，可能对有明毯的物种眼睛的进一步生理测量很重要。(b) 在这个特定的动物模型中，明毯细胞本身可能在视网膜变性期间对脉络膜毛细血管和视网膜色素上皮（RPE）具有保护作用。即使在视网膜变性的晚期，明毯覆盖区域的RPE和脉络膜毛细血管也未受影响，而无微毯区域则出现了RPE和毛细血管的丧失。
