Biavasco F, Manso E, Varaldo P E
Institute of Microbiology, University of Ancona Medical School, Italy.
Antimicrob Agents Chemother. 1991 Jan;35(1):195-7. doi: 10.1128/AAC.35.1.195.
Seventy strains of Clostridium difficile, all isolated from symptomatic patients, were found to be uniformly susceptible to ramoplanin, a new glycolipodepsipeptide antibiotic, and to four glycopeptides (vancomycin, teicoplanin, and two semisynthetic teicoplanin derivatives). Ramoplanin is recommended for further evaluation in the treatment of C. difficile-associated disease.
从有症状的患者中分离出的70株艰难梭菌,被发现对一种新型糖脂缩肽抗生素雷莫拉宁以及四种糖肽(万古霉素、替考拉宁和两种半合成替考拉宁衍生物)均普遍敏感。推荐对雷莫拉宁用于治疗艰难梭菌相关疾病进行进一步评估。