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In vitro activities of ramoplanin and four glycopeptide antibiotics against clinical isolates of Clostridium difficile.雷莫拉宁和四种糖肽类抗生素对艰难梭菌临床分离株的体外活性
Antimicrob Agents Chemother. 1991 Jan;35(1):195-7. doi: 10.1128/AAC.35.1.195.
2
In-vitro activity of vancomycin, teicoplanin, daptomycin, ramoplanin, MDL 62873 and other agents against staphylococci, enterococci and Clostridium difficile.万古霉素、替考拉宁、达托霉素、雷莫拉宁、MDL 62873及其他药物对葡萄球菌、肠球菌和艰难梭菌的体外活性。
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[Susceptibility of Clostridium difficile strains to teicoplanin and ramoplanin].
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A Review of Experimental and Off-Label Therapies for Clostridium difficile Infection.艰难梭菌感染的实验性和非标签疗法综述
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In vitro activities of ramoplanin, teicoplanin, vancomycin, linezolid, bacitracin, and four other antimicrobials against intestinal anaerobic bacteria.雷莫拉宁、替考拉宁、万古霉素、利奈唑胺、杆菌肽及其他四种抗菌药物对肠道厌氧菌的体外活性
Antimicrob Agents Chemother. 2003 Jul;47(7):2334-8. doi: 10.1128/AAC.47.7.2334-2338.2003.
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Antimicrobial susceptibilities and serogroups of clinical strains of Clostridium difficile isolated in France in 1991 and 1997.1991年和1997年在法国分离出的艰难梭菌临床菌株的抗菌药敏性及血清群
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Some chemical and physical characteristics of pantomycin, and antiobiotic isolated from Streptomyces hygroscopicus.泛霉素的一些化学和物理特性，一种从吸水链霉菌中分离出的抗生素。
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In vitro activity of A-16686, a potential antiplaque agent.A-16686（一种潜在的抗牙菌斑剂）的体外活性
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Treatment of antibiotic-associated colitis with vancomycin.用万古霉素治疗抗生素相关性结肠炎。
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In vitro activity of teichomycin and vancomycin alone and in combination with rifampin.替考拉宁和万古霉素单独及与利福平联合使用时的体外活性。
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Recovery of resistant enterococci during vancomycin prophylaxis.万古霉素预防期间耐万古霉素肠球菌的恢复情况。
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In vitro evaluation of ramoplanin (MDL 62198, A 16686).瑞莫拉宁（MDL 62198，A 16686）的体外评估
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雷莫拉宁和四种糖肽类抗生素对艰难梭菌临床分离株的体外活性

In vitro activities of ramoplanin and four glycopeptide antibiotics against clinical isolates of Clostridium difficile.

作者信息

Biavasco F, Manso E, Varaldo P E

机构信息

Institute of Microbiology, University of Ancona Medical School, Italy.

出版信息

Antimicrob Agents Chemother. 1991 Jan;35(1):195-7. doi: 10.1128/AAC.35.1.195.

DOI:10.1128/AAC.35.1.195
PMID:1826593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC244968/
Abstract

Seventy strains of Clostridium difficile, all isolated from symptomatic patients, were found to be uniformly susceptible to ramoplanin, a new glycolipodepsipeptide antibiotic, and to four glycopeptides (vancomycin, teicoplanin, and two semisynthetic teicoplanin derivatives). Ramoplanin is recommended for further evaluation in the treatment of C. difficile-associated disease.

摘要

从有症状的患者中分离出的70株艰难梭菌，被发现对一种新型糖脂缩肽抗生素雷莫拉宁以及四种糖肽（万古霉素、替考拉宁和两种半合成替考拉宁衍生物）均普遍敏感。推荐对雷莫拉宁用于治疗艰难梭菌相关疾病进行进一步评估。