雷莫拉宁和四种糖肽类抗生素对艰难梭菌临床分离株的体外活性
In vitro activities of ramoplanin and four glycopeptide antibiotics against clinical isolates of Clostridium difficile.
作者信息
Biavasco F, Manso E, Varaldo P E
机构信息
Institute of Microbiology, University of Ancona Medical School, Italy.
出版信息
Antimicrob Agents Chemother. 1991 Jan;35(1):195-7. doi: 10.1128/AAC.35.1.195.
Abstract
Seventy strains of Clostridium difficile, all isolated from symptomatic patients, were found to be uniformly susceptible to ramoplanin, a new glycolipodepsipeptide antibiotic, and to four glycopeptides (vancomycin, teicoplanin, and two semisynthetic teicoplanin derivatives). Ramoplanin is recommended for further evaluation in the treatment of C. difficile-associated disease.
摘要
从有症状的患者中分离出的70株艰难梭菌，被发现对一种新型糖脂缩肽抗生素雷莫拉宁以及四种糖肽（万古霉素、替考拉宁和两种半合成替考拉宁衍生物）均普遍敏感。推荐对雷莫拉宁用于治疗艰难梭菌相关疾病进行进一步评估。
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