Armstrong Richard A
Vision Sciences, Aston University, Birmingham, UK.
Clin Exp Optom. 2008 Mar;91(2):129-38. doi: 10.1111/j.1444-0938.2007.00211.x.
Parkinson's disease (PD) is a common disorder of middle-aged and elderly people, in which there is degeneration of the extra-pyramidal motor system. In some patients, the disease is associated with a range of visual signs and symptoms, including defects in visual acuity, colour vision, the blink reflex, pupil reactivity, saccadic and smooth pursuit movements and visual evoked potentials. In addition, there may be psychophysical changes, disturbances of complex visual functions such as visuospatial orientation and facial recognition, and chronic visual hallucinations. Some of the treatments associated with PD may have adverse ocular reactions. If visual problems are present, they can have an important effect on overall motor function, and quality of life of patients can be improved by accurate diagnosis and correction of such defects. Moreover, visual testing is useful in separating PD from other movement disorders with visual symptoms, such as dementia with Lewy bodies (DLB), multiple system atrophy (MSA) and progressive supranuclear palsy (PSP). Although not central to PD, visual signs and symptoms can be an important though obscure aspect of the disease and should not be overlooked.
帕金森病(PD)是一种常见于中老年人的疾病,其锥体外系运动系统会发生退化。在一些患者中,该疾病与一系列视觉体征和症状相关,包括视力缺陷、色觉、眨眼反射、瞳孔反应、扫视和平滑跟踪运动以及视觉诱发电位。此外,可能存在心理物理学变化、复杂视觉功能障碍,如视觉空间定向和面部识别障碍,以及慢性视幻觉。一些与帕金森病相关的治疗可能会有不良眼部反应。如果存在视觉问题,它们会对整体运动功能产生重要影响,准确诊断和纠正此类缺陷可改善患者的生活质量。此外,视觉测试有助于将帕金森病与其他有视觉症状的运动障碍区分开来,如路易体痴呆(DLB)、多系统萎缩(MSA)和进行性核上性麻痹(PSP)。虽然视觉体征和症状并非帕金森病的核心,但它们可能是该疾病一个重要却容易被忽视的方面,不应被忽视。