O'Sullivan M, Nic Suibhne T, Cox G, Healy M, O'Morain C
Department of Clinical Medicine, Trinity Centre for Health Sciences, Adelaide and Meath Hospital, Dublin 24, Ireland.
Ir J Med Sci. 2008 Jun;177(2):131-4. doi: 10.1007/s11845-008-0129-z. Epub 2008 Feb 15.
Specific sub-groups of the population, such as older people, are at increased risk of poor vitamin D status. There is growing evidence, however, that vitamin D insufficiency may be a more widespread problem.
To determine the prevalence of vitamin D insufficiency in a group of healthy Irish adults.
Serum 25-hydroxyvitamin D was measured by radioimmunoassay in 70 healthy Irish adults working in South Dublin.
Overall, half of the group (51%) had vitamin D insufficiency; this was more pronounced in wintertime, with prevalence rising to 58%. Winter was a significant negative predictor of serum 25-OH D levels. Sixteen percent of the participants reported taking a vitamin D-containing supplement (multivitamin), but this did not significantly influence the serum 25-OH D levels.
Vitamin D insufficiency is not confined to "at-risk groups" and is likely to be prevalent in the general public in Ireland, especially in wintertime.
特定人群亚组，如老年人，维生素D水平低下的风险增加。然而，越来越多的证据表明，维生素D不足可能是一个更广泛的问题。
确定一组健康爱尔兰成年人中维生素D不足的患病率。
采用放射免疫分析法测定了70名在都柏林南部工作的健康爱尔兰成年人的血清25-羟维生素D水平。
总体而言，该组中有一半（51%）存在维生素D不足；这在冬季更为明显，患病率升至58%。冬季是血清25-OH D水平的显著负预测因子。16%的参与者报告服用含维生素D的补充剂（复合维生素），但这对血清25-OH D水平没有显著影响。
维生素D不足并不局限于“高危人群”，在爱尔兰普通公众中可能很普遍，尤其是在冬季。
