浆果楝茎中的萜类化合物。

Terpenoids from the stems of Cipadessa baccifera.

作者信息

Lin Li-Gen, Tang Chun-Ping, Ke Chang-Qiang, Zhang Yi, Ye Yang

机构信息

State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zu-Chong-Zhi Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.

出版信息

J Nat Prod. 2008 Apr;71(4):628-32. doi: 10.1021/np070674o. Epub 2008 Feb 15.

DOI:10.1021/np070674o

PMID:18275151

Abstract

In our systematical investigation on Chinese Meliaceae plants, the stems of Cipadessa baccifera collected in Yunnan province were studied. Two new tetranortriterpenoids, cipadessalide ( 1) and rubralin D ( 2), one new pregnane, 3beta,4beta-dihydroxy-2beta-acetoxypregnan-16-one ( 3), and two new sesquiterpenoids, bacciferins A ( 4) and B ( 5), along with 10 known compounds were isolated. Their structures were elucidated by 1D and 2D NMR spectra and other spectroscopic studies, as well as chemical conversion.

摘要

在我们对中国楝科植物的系统研究中，对采自云南省的浆果楝的茎进行了研究。分离得到了两个新的四降三萜类化合物，浆果楝内酯（1）和红椿灵D（2），一个新的孕甾烷类化合物，3β,4β - 二羟基 - 2β - 乙酰氧基孕甾 - 16 - 酮（3），以及两个新的倍半萜类化合物，浆果楝素A（4）和浆果楝素B（5），同时还分离得到了10个已知化合物。通过一维和二维核磁共振光谱以及其他光谱研究和化学转化确定了它们的结构。