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人类面部组织同种异体移植中的伦理考量。

Ethical considerations in human facial tissue allotransplantation.

作者信息

Barker John H, Brown Charles S, Cunningham Michael, Wiggins Osborne, Furr Allen, Maldonado Claudio, Banis Joseph C

机构信息

Department of Surgery, University of Louisville, Louisville, KY 40202, USA.

出版信息

Ann Plast Surg. 2008 Jan;60(1):103-9. doi: 10.1097/SAP.0b013e31804bdf42.

DOI:10.1097/SAP.0b013e31804bdf42
PMID:18281806
Abstract

BACKGROUND

Human facial tissue allotransplantation is now a clinical reality. Proponents of this new treatment contend that the benefits outweigh the risks, while the critics argue they do not. This debate has been presented in great detail in the bioethics literature but has not been brought to the attention of the plastic surgery community.

METHODS

The purpose of this paper is to provide a synopsis of the key issues being debated in facial transplantation by presenting to the plastic surgery community a synopsis of an ethical debate published in the 2004 summer issue of the American Journal of Bioethics.

RESULTS

Presented is a set of ethical guidelines for facial transplantation in the form of a "target article." Alongside this are written commentaries from 15 experts in related fields, along with responses to these commentaries. Together, this discussion makes up a landmark exercise in open display and public and professional discussion and evaluation and serves as a comprehensive list of the major ethical issues being debated today in the field of facial tissue allotransplantation.

CONCLUSIONS

Plastic surgeons play a central role in the care of facially disfigured patients and will therefore lead the introduction of facial tissue allotransplantation into the clinical arena. Consequently, it is important that they be aware of, and indeed that they play a key role in forming, the debate surrounding this new treatment. It is with this in mind that we present this synopsis to the plastic surgery readership.

摘要

背景

人类面部组织同种异体移植如今已成为临床现实。这种新疗法的支持者认为其益处大于风险,而批评者则认为并非如此。这场辩论在生物伦理学文献中已有详尽阐述,但尚未引起整形外科学界的关注。

方法

本文旨在通过向整形外科学界呈现发表于《美国生物伦理学杂志》2004年夏季刊的一场伦理辩论概要,来概述面部移植中正在辩论的关键问题。

结果

以“目标文章”的形式呈现了一套面部移植的伦理准则。与之相伴的是15位相关领域专家的书面评论以及对这些评论的回应。这场讨论共同构成了一次公开展示、公众及专业讨论与评估的里程碑式活动,并作为面部组织同种异体移植领域当前正在辩论的主要伦理问题的全面清单。

结论

整形外科医生在面部畸形患者的护理中起着核心作用,因此将引领面部组织同种异体移植引入临床领域。所以,他们了解围绕这种新疗法的辩论并在其中发挥关键作用非常重要。正是出于这一考虑,我们向整形外科读者呈现此概要。

相似文献

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Ethical considerations in human facial tissue allotransplantation.人类面部组织同种异体移植中的伦理考量。
Ann Plast Surg. 2008 Jan;60(1):103-9. doi: 10.1097/SAP.0b013e31804bdf42.
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Facial transplantation: understanding the interests of patients and hurdles to informed consent.
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Allotransplantation of the face: how close are we?面部同种异体移植:我们进展到什么程度了?
Clin Plast Surg. 2005 Jul;32(3):401-9, vii. doi: 10.1016/j.cps.2005.02.003.
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[Review on progress of facial allotransplantation].[面部同种异体移植研究进展综述]
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Ethical considerations in face transplantation: ethical issues related to inclusion criteria for face transplant candidates.面部移植中的伦理考量:与面部移植候选者纳入标准相关的伦理问题。
Arch Immunol Ther Exp (Warsz). 2011 Jun;59(3):157-9. doi: 10.1007/s00005-011-0121-6. Epub 2011 Mar 27.
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Informed consent for facial transplantation.面部移植的知情同意书。
Transpl Int. 2006 Nov;19(11):861-7. doi: 10.1111/j.1432-2277.2006.00358.x.
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Face transplantation: a review of the technical, immunological, psychological and clinical issues with recommendations for good practice.面部移植:对技术、免疫、心理及临床问题的综述并提出良好实践建议
Transplantation. 2007 Jan 27;83(2):109-28. doi: 10.1097/01.tp.0000254201.89012.ae.
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Facial transplantation in a new era: what are the ethical implications?新时代的面部移植:伦理意义何在?
Curr Opin Otolaryngol Head Neck Surg. 2009 Aug;17(4):274-8. doi: 10.1097/MOO.0b013e32832cba57.
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Plastic surgeon's risk acceptance in facial transplantation.整形外科医生对面部移植的风险接受度
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