Contardi I
Divisione di Pediatria, Ospedale Civico di Codogno, MI.
Clin Ter. 1991 Mar 31;136(6):409-13.
Amoxycillin is currently the most widely used antibiotic in pediatrics. It is known that this antibiotic, as well as other kinds of antimicrobial treatments, may produce variations in the bowel ecosystem. A controlled randomised clinical trial was performed using commercially available fermented milk products in infants who had received an oral treatment with amoxycillin for an average of ten days. 40 children have been examined, randomly divided into two groups of twenty. Group 1 received treatment with antibiotic plus lactobacilli. Group 2 received only amoxycillin. At the end of the trial infants of group 1 showed a lower frequency of stool passages and more fully-formed feces, while patients of group 2 presented an increased frequency of gastrointestinal disorders. On the basis of the results obtained it is possible to conclude that oral bacterial therapy with lactobacilli is efficacious in preventing diarrhea from amoxycillin in infancy.
阿莫西林是目前儿科中使用最广泛的抗生素。众所周知，这种抗生素以及其他种类的抗菌治疗可能会导致肠道生态系统的变化。我们对平均接受了十天口服阿莫西林治疗的婴儿进行了一项对照随机临床试验，使用市售发酵乳制品。共检查了40名儿童，随机分为两组，每组20人。第一组接受抗生素加乳酸菌治疗。第二组仅接受阿莫西林治疗。试验结束时，第一组婴儿的排便频率较低，粪便成型更好，而第二组患者的胃肠道疾病发生率增加。根据所获得的结果可以得出结论，乳酸菌口服细菌疗法在预防婴儿因阿莫西林导致的腹泻方面是有效的。
