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叶黄素与老年人年龄相关性眼部疾病:综述

Lutein and age-related ocular disorders in the older adult: a review.

作者信息

Renzi Lisa M, Johnson Elizabeth J

机构信息

Vision Science Laboratory, University of Georgia, Athens 30602, USA.

出版信息

J Nutr Elder. 2007;26(3-4):139-57. doi: 10.1300/j052v26n03_07.

Abstract

Lutein, a carotenoid found in dark green, leafy vegetables, has been implicated as being protective against the acquired ocular diseases, such as cataracts and age-related macular degeneration. In the eye, lutein may act as an antioxidant and as a blue light filter to protect the underlying tissues from phototoxic damage. Average intakes of lutein in the U.S. are below levels associated with eye disease prevention. Therefore, increased intakes of food sources rich in lutein may be warranted. Age-related factors, such as increased inflammation and body fat, are also related to increased risk of age-related eye disease. The mechanism by which these factors are related to risk may be partially due to adverse effects on lutein status.

摘要

叶黄素是一种存在于深绿色叶菜中的类胡萝卜素,被认为对预防诸如白内障和年龄相关性黄斑变性等后天性眼部疾病具有保护作用。在眼睛中,叶黄素可能作为一种抗氧化剂和蓝光过滤器,保护下层组织免受光毒性损伤。美国叶黄素的平均摄入量低于与预防眼部疾病相关的水平。因此,可能有必要增加富含叶黄素的食物来源的摄入量。与年龄相关的因素,如炎症增加和体脂增加,也与年龄相关性眼病风险增加有关。这些因素与风险相关的机制可能部分归因于对叶黄素状态的不利影响。

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