Barraza Román A, Poeschla Eric M
Molecular Medicine Program, Guggenheim 18, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, United States.
Vet Immunol Immunopathol. 2008 May 15;123(1-2):23-31. doi: 10.1016/j.vetimm.2008.01.009. Epub 2008 Jan 19.
Lentiviral vectors are useful for gene transfer to dividing and nondividing cells. Feline immunodeficiency virus (FIV) vectors transduce most human cell types with good efficiency and may have advantages for clinical gene therapy applications. This article reviews significant progress in the development and refinement of FIV vector systems.
慢病毒载体对于将基因转移到分裂细胞和非分裂细胞中很有用。猫免疫缺陷病毒（FIV）载体能高效转导大多数人类细胞类型，在临床基因治疗应用中可能具有优势。本文综述了FIV载体系统开发与优化方面取得的重大进展。
