Jandeck C, Kellner U, Lorenz B, Seiberth V
Artemis Zentren Dillenburg/Frankfurt, Frankfurt.
Klin Monbl Augenheilkd. 2008 Feb;225(2):123-30. doi: 10.1055/s-2008-1027168.
These revised guidelines replace the previous guidelines on the screening of preterm infants for retinopathy of prematurity (ROP) that were published in 1999. Recently published research provided the impetus for this revision. These guidelines propose the following criteria for an efficient screening programme for the early detection and treatment of ROP in Germany: Inclusion criteria for ROP screening: All preterm infants with a gestational age of less than 32 weeks (if gestational age is unknown; of <1500 g birth weight) should be examined. In addition, all preterm infants with 32-36 weeks gestational age are included if postnatal oxygen was supplemented for more than 3 days. The first examination should be performed within the 5(th) week of postnatal age (day 36-42), but not prior to 31 weeks gestational age. Indications for laser photocoagulation: in Zone I: 1. any stage with "plus disease", 2. stage 3 without "plus disease." In Zone II: stage 3 with extraretinal proliferations in 5 continuous or 8 cumulative clock hours in combination with "plus-disease". In certain cases an earlier treatment may be indicated.
这些修订后的指南取代了1999年发布的关于早产儿视网膜病变(ROP)筛查的先前指南。最近发表的研究为此次修订提供了动力。这些指南提出了在德国进行ROP早期检测和治疗的有效筛查计划的以下标准:ROP筛查的纳入标准:所有孕周小于32周的早产儿(如果孕周未知;出生体重<1500克)均应接受检查。此外,所有孕周为32 - 36周且出生后吸氧超过3天的早产儿也应纳入筛查。首次检查应在出生后第5周(第36 - 42天)内进行,但不得早于孕周31周。激光光凝治疗指征:在I区:1. 任何阶段伴有“plus病”;2. 无“plus病”的3期。在II区:3期伴有视网膜外增殖连续5个或累计8个钟点且伴有“plus病”。在某些情况下,可能需要更早进行治疗。