Petersilka Gregor, Faggion Clovis Mariano, Stratmann Udo, Gerss Joachim, Ehmke Benjamin, Haeberlein Ingo, Flemmig Thomas F
Department of Periodontology, Westphalian Wilhelm University of Muenster, Muenster, Germany.
J Clin Periodontol. 2008 Apr;35(4):324-32. doi: 10.1111/j.1600-051X.2007.01195.x. Epub 2008 Feb 20.
Safety and efficacy of glycine powder air-polishing (GPAP) in removing subgingival biofilm have been previously demonstrated. The hypothesis that GPAP results in less gingival erosion than sodium bicarbonate air-polishing (SBAP) or hand-instrumentation was assessed.
In each of 10 patients, eight teeth with a residual probing depth of at least 5 mm following initial periodontal therapy were randomly assigned to the following interventions: GPAP (test), SBAP (positive control), hand-instrumentation (positive control), or no treatment (negative control). In each group, gingival biopsies were taken immediately after instrumentation and one 14 days later. Damaged gingival epithelium (GE) was assessed by light microscopy and quantified by a histological score (values 1-4). Differences between groups were evaluated using the marginal homogeneity test.
GPAP resulted in minor erosions of the GE (scores 1 and 2), whereas positive control specimens displayed moderate to severe erosions (scores 2-4). Differences between GPAP and positive controls were significant (p<0.05). Fourteen days following instrumentation GE under assessment was found to be intact in all groups.
The data indicated that GPAP results in less gingival erosion than SBAP or hand instrumentation, further supporting the safety of this new debridement technique.
先前已证明甘氨酸粉末空气抛光(GPAP)在去除龈下生物膜方面的安全性和有效性。评估了GPAP导致的牙龈侵蚀比碳酸氢钠空气抛光(SBAP)或手工器械操作更少的假设。
在10名患者中,将初始牙周治疗后探诊深度至少为5mm的8颗牙齿随机分配至以下干预措施:GPAP(试验组)、SBAP(阳性对照组)、手工器械操作(阳性对照组)或不治疗(阴性对照组)。每组在器械操作后立即及14天后进行牙龈活检。通过光学显微镜评估受损的牙龈上皮(GE),并通过组织学评分(1-4分)进行量化。使用边际齐性检验评估组间差异。
GPAP导致GE出现轻微侵蚀(评分为1分和2分),而阳性对照标本显示中度至重度侵蚀(评分为2-4分)。GPAP与阳性对照组之间的差异具有统计学意义(p<0.05)。器械操作14天后,所有组中接受评估的GE均完好无损。
数据表明,GPAP导致的牙龈侵蚀比SBAP或手工器械操作更少,进一步支持了这种新的清创技术的安全性。