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小RNA:维持干细胞的秩序

Small RNAs: keeping stem cells in line.

作者信息

Stadler Bradford M, Ruohola-Baker Hannele

机构信息

Department of Biochemistry and Institute for Stem Cell and Regenerative Medicine, University of Washington, 1705 NE Pacific Street, Health Science Building, Room J-587, Seattle, WA 98195, USA.

出版信息

Cell. 2008 Feb 22;132(4):563-6. doi: 10.1016/j.cell.2008.02.005.

Abstract

Stem cells and RNA silencing have emerged as areas of intense interest for both basic and clinical research. Recently these fields have converged with reports implicating small regulatory RNAs in the maintenance and pluripotency of stem cells.

摘要

干细胞和RNA沉默已成为基础研究和临床研究中备受关注的领域。最近,这些领域出现了交叉,有报道表明小调节RNA与干细胞的维持和多能性有关。

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