Moran Gregory J, Talan David A, Abrahamian Fredrick M
David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA.
Infect Dis Clin North Am. 2008 Mar;22(1):145-87, vii. doi: 10.1016/j.idc.2007.12.003.
A biological terrorism event could have a large impact on the general population and health care system. The impact of an infectious disaster will most likely be great to emergency departments, and the collaboration between emergency and infectious disease specialists will be critical in developing an effective response. A bioterrorism event is a disaster that requires specific preparations beyond the usual medical disaster planning. An effective response would include attention to infection control issues and plans for large-scale vaccination or antimicrobial prophylaxis. This article addresses some general issues related to preparing an effective response to a biological terrorism event. It will also review organisms and toxins that could be used in biological terrorism, including clinical features, management, diagnostic testing, and infection control.
生物恐怖主义事件可能会对普通民众和医疗保健系统产生重大影响。传染病灾难对急诊科的影响很可能很大,而急诊科与传染病专家之间的合作对于制定有效的应对措施至关重要。生物恐怖主义事件是一种灾难,需要进行超出常规医疗灾难规划的特殊准备。有效的应对措施将包括关注感染控制问题以及大规模疫苗接种或抗菌预防计划。本文讨论了与准备有效应对生物恐怖主义事件相关的一些一般性问题。它还将回顾可能用于生物恐怖主义的生物制剂和毒素,包括临床特征、管理、诊断检测和感染控制。