Du Hong, Antonuk Larry E, El-Mohri Youcef, Zhao Qihua, Su Zhong, Yamamoto Jin, Wang Yi
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA.
Phys Med Biol. 2008 Mar 7;53(5):1325-51. doi: 10.1088/0031-9155/53/5/011. Epub 2008 Feb 14.
Active matrix, flat-panel x-ray imagers based on a-Si:H thin-film transistors offer many advantages and are widely utilized in medical imaging applications. Unfortunately, the detective quantum efficiency (DQE) of conventional flat-panel imagers incorporating scintillators or a-Se photoconductors is significantly limited by their relatively modest signal-to-noise ratio, particularly in applications involving low x-ray exposures or high spatial resolution. For this reason, polycrystalline HgI2 is of considerable interest by virtue of its low effective work function, high atomic number and the possibility of large-area deposition. In this study, a detailed investigation of the properties of prototype, flat-panel arrays coated with two forms of this high-gain photoconductor are reported. Encouragingly, high x-ray sensitivity, low dark current and spatial resolution close to the theoretical limits were observed from a number of prototypes. In addition, input-quantum-limited DQE performance was measured from one of the prototypes at relatively low exposures. However, high levels of charge trapping, lag and polarization, as well as pixel-to-pixel variations in x-ray sensitivity are of concern. While the results of the current study are promising, further development will be required to realize prototypes exhibiting the characteristics necessary to allow practical implementation of this approach.
基于非晶硅氢化薄膜晶体管的有源矩阵平板X射线成像器具有诸多优势,在医学成像应用中得到广泛应用。不幸的是,采用闪烁体或非晶硒光电导体的传统平板成像器的探测量子效率(DQE)因其相对较低的信噪比而受到显著限制,尤其是在涉及低X射线曝光或高空间分辨率的应用中。因此,多晶碘化汞因其低有效功函数、高原子序数以及大面积沉积的可能性而备受关注。在本研究中,报告了对涂覆有这种高增益光电导体两种形式的原型平板阵列特性的详细研究。令人鼓舞的是,从多个原型中观察到了高X射线灵敏度、低暗电流以及接近理论极限的空间分辨率。此外,在相对低曝光条件下从其中一个原型测量到了输入量子极限的DQE性能。然而,高水平的电荷俘获、滞后和极化,以及X射线灵敏度的像素间变化令人担忧。虽然当前研究结果很有前景,但要实现具有允许该方法实际应用所需特性的原型,还需要进一步发展。