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挪威母婴队列研究(MoBa)中地中海式饮食与女性早产风险:一项前瞻性队列研究

Mediterranean-type diet and risk of preterm birth among women in the Norwegian Mother and Child Cohort Study (MoBa): a prospective cohort study.

作者信息

Haugen Margaretha, Meltzer Helle Margrete, Brantsaeter Anne Lise, Mikkelsen Tina, Osterdal Marie Louise, Alexander Jan, Olsen Sjurdur F, Bakketeig Leiv

机构信息

Division of Environmental Medicine, Department of Food Toxicology, Norwegian Institute of Public Health, Oslo, Nydalen, Norway.

出版信息

Acta Obstet Gynecol Scand. 2008;87(3):319-24. doi: 10.1080/00016340801899123.

Abstract

BACKGROUND

Mediterranean diet has been shown to reduce the incidence of preterm birth. We wanted to investigate whether a Mediterranean-type diet (MD) could be associated with a lower risk of preterm birth in the Norwegian Mother and Child Cohort Study (MoBa).

METHODS

The data collection was conducted as part of MoBa at the Norwegian Institute of Public Health. In MoBa, women answer a Food Frequency Questionnaire (FFQ) at week 18-22 of pregnancy. The MD criteria were intake of fish > or =2 times a week, fruit and vegetables > or =5 times a day, use of olive/canola oil, red meat intake < or = times 2 a week, and < or =2 cups of coffee a day.

RESULTS

A total of 569 women (2.2%) met the MD criteria, 25,397 women (97.2%) met 1-4 criteria, and 159 women (0.01%) met none of the MD criteria. The number of preterm births in the MD group was 26 (4.6%), in those who met 1-4 criteria it was 1,148 (4.5%), and in those who met none of the criteria it was 10 (6.3%). The women who met the MD criteria did not have reduced risk of preterm birth compared with women meeting none of the MD criteria (OR: 0.73; 95% CI: 0.32, 1.68). Intake of fish twice or more a week was associated with a lower risk of preterm birth (OR: 0.84; 95% CI: 0.74, 0.95).

CONCLUSIONS

The women who fulfilled the criteria of a MD did not have a reduced risk of preterm birth.

摘要

背景

地中海饮食已被证明可降低早产发生率。我们想在挪威母婴队列研究(MoBa)中调查地中海式饮食(MD)是否与较低的早产风险相关。

方法

数据收集是挪威公共卫生研究所MoBa研究的一部分。在MoBa研究中,女性在怀孕第18 - 22周时回答一份食物频率问卷(FFQ)。MD标准为每周吃鱼≥2次、每天吃水果和蔬菜≥5次、使用橄榄油/菜籽油、每周吃红肉≤2次以及每天喝咖啡≤2杯。

结果

共有569名女性(2.2%)符合MD标准,25397名女性(97.2%)符合1 - 4条标准,159名女性(0.01%)不符合任何MD标准。MD组的早产人数为26人(4.6%),符合1 - 4条标准的为1148人(4.5%),不符合任何标准的为10人(6.3%)。与不符合任何MD标准的女性相比,符合MD标准的女性早产风险并未降低(比值比:0.73;95%置信区间:0.32,1.68)。每周吃鱼两次或更多与较低的早产风险相关(比值比:0.84;95%置信区间:0.74,0.95)。

结论

符合MD标准的女性早产风险并未降低。

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