Fel'dblium I V, Basova N N, Koza N M, Markovich N I, Ivenskikh V I, Il'ina A N
Zh Mikrobiol Epidemiol Immunobiol. 1991 Apr(4):45-7.
The dependence of immune response on commonly observed immunity characteristics prior to immunization has been established on the basis of the study of the kinetics of immune response in adults receiving injections of adsorbed diphtheria-tetanus (DT) toxoid with reduced antigen content, both for routine immunization and on epidemiological indications. The necessity of the practical use of immunological screening for the differentiated approach to the choice of a suitable preparation (adsorbed diphtheria toxoid, adsorbed DT toxoid or adsorbed DT toxoid with reduced antigen content) and immunization schedule for adults, especially in epidemic foci, has been substantiated.
在接受抗原含量降低的吸附白喉-破伤风（DT）类毒素注射的成年人中，针对常规免疫和流行病学指征，对免疫反应动力学进行了研究，从而确立了免疫反应对免疫前常见免疫特征的依赖性。已经证实，在实际应用中，有必要进行免疫学筛查，以便采用差异化方法为成年人选择合适的制剂（吸附白喉类毒素、吸附DT类毒素或抗原含量降低的吸附DT类毒素）和免疫程序，尤其是在疫源地。
